147539-23-9

Basic information

• Product Name: 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER
• Synonyms: 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER;1-Boc-4-(6-chloro-5-nitro-4-pyrimidinyl)piperazine;tert-Butyl 4-(6-chloro-5-nitropyrimidin-4-yl)piperazine-1-carboxylate;1-Boc-4-(6-Chloro-5-nitro-4-pyrimidinyl)
• CAS NO: 147539-23-9
• Molecular Formula: C13H18ClN5O4
• Molecular Weight: 343.77
• Mol File: 147539-23-9.mol

Chemical Properties

• Boiling Point: 501.5°C at 760 mmHg
• Flash Point: 257.1°C
• Appearance: /
• Density: 1.374g/cm³
• Vapor Pressure: 3.45E-10mmHg at 25°C
• Refractive Index: 1.573
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 0.01±0.35(Predicted)
• CAS DataBase Reference: 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER(147539-23-9)
• EPA Substance Registry System: 4-(6-CHLORO-5-NITRO-4-PYRIMIDINYL)-1-PIPERAZINECARBOXYLIC ACID 1,1-DIMETHYLETHYL ESTER(147539-23-9)

Safety Data

• Hazardous Substances Data: 147539-23-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research:
4-(6-Chloro-5-nitro-4-pyrimidinyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester is used as a key intermediate in the synthesis of various pharmaceuticals for [application reason]. Its unique structure and potent properties make it a valuable component in the development of new drugs.
Used in Scientific Research:
In the field of scientific research, 4-(6-Chloro-5-nitro-4-pyrimidinyl)-1-piperazinecarboxylic Acid 1,1-Dimethylethyl Ester is used as a research compound for [application reason]. Its distinctive chemical properties allow researchers to explore its potential applications and interactions with other compounds, furthering our understanding of its capabilities and limitations.

InChI:InChI=1/C13H18ClN5O4/c1-13(2,3)23-12(20)18-6-4-17(5-7-18)11-9(19(21)22)10(14)15-8-16-11/h8H,4-7H2,1-3H3

Upstream product

• 4316-93-2 4,6-dichloro-5-nitropyrimidine 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Relevant articles and documents

1,3-DIHYDROIMIDAZOLE FUSED-RING COMPOUND

The objective of this invention is to provide novel compounds that show excellent DPPIV-inhibiting activity. The present invention provides compounds represented by the general formula (I), salts thereof, or hydrates thereof, [wherein,T1 stands for a monocyclic or bicyclic 4 to 12-membered heterocycle having 1 or 2 nitrogen atoms in the ring, which may have substituents; in formula (I), the following formula represents a double bond or a single bond; X3 denotes an oxygen atom or a sulfur atom; X1 denotes a C2-6 alkynyl group which may have substituents; Z1 denotes a nitrogen atom or the formula -CR3=; Z2 and Z3 each independently denote a nitrogen atom, the formula -CR1=, a carbonyl group, or the formula -NR2-; R1, R2, R3, and X2 each independently denote a C1-6 alkyl group which may have substituents, and such].

Substituted indoles as anti-AIDS pharmaceuticals

Substituted indoles of formula (I) STR1 are useful anti-AIDS pharmaceuticals.

Anti-aids piperazines

The present invention includes diaromatic substituted heterocyclic compounds (III) STR1 which are useful in treating individuals infected with the HIV virus. The invention includes certain previously generically disclosed anti-AIDS piperazinyl compounds (V) and a method of treating HIV infected individuals with the indoles of formula (V) and the anti-AIDS amines (X).