14770-51-5

Basic information

• Product Name: PROPIONIC-2,2-D2 ACID
• Synonyms: PROPIONIC-2,2-D2 ACID;PROPIONIC-2,2-D2 ACID-D;PROPIONIC ACID (2,2-D2);PROPIONIC-2,2-D2 ACID-D, 99 ATOM % D
• CAS NO: 14770-51-5
• Molecular Formula: C3H3D3O2
• Molecular Weight: 77.1
• Product Categories: Alphabetical Listings;P;Stable Isotopes
• Mol File: 14770-51-5.mol

Chemical Properties

• Melting Point: −24-−23 °C(lit.)
• Boiling Point: 141 °C(lit.)
• Flash Point: 125 °F
• Appearance: /
• Density: 1.03 g/mL at 25 °C(lit.)
• Vapor Pressure: 4.23mmHg at 25°C
• Refractive Index: n20/D 1.386(lit.)
• CAS DataBase Reference: PROPIONIC-2,2-D2 ACID(CAS DataBase Reference)
• NIST Chemistry Reference: PROPIONIC-2,2-D2 ACID(14770-51-5)
• EPA Substance Registry System: PROPIONIC-2,2-D2 ACID(14770-51-5)

Safety Data

• Hazard Codes: C
• Statements: 34
• Safety Statements: 23-36-45
• RIDADR: UN 3463 8/PG 2
• WGK Germany: 3
• Hazardous Substances Data: 14770-51-5(Hazardous Substances Data)

Usage

Uses

Used in Chemical and Pharmaceutical Production:
PROPIONIC-2,2-D2 ACID is used as a key intermediate in the synthesis of various chemicals and pharmaceuticals, leveraging its carboxylic acid properties for the formation of esters, amides, and other functional groups.
Used in NMR Spectroscopy:
In the field of NMR spectroscopy, PROPIONIC-2,2-D2 ACID is utilized as a deuterated solvent or reagent to enhance the resolution and sensitivity of the analysis, providing clearer insights into molecular structures and interactions.
Used in Analytical Techniques:
PROPIONIC-2,2-D2 ACID is employed in other analytical techniques that benefit from deuterium labeling, such as mass spectrometry and infrared spectroscopy, to improve the accuracy and precision of measurements.
Used in Metabolic Pathway Studies:
In biological research, PROPIONIC-2,2-D2 ACID is used as a tracer compound in the study of metabolic pathways, helping to elucidate the mechanisms of biochemical processes and the regulation of cellular functions.
Used in Biochemical Process Regulation:
PROPIONIC-2,2-D2 ACID aids in understanding the regulation of biochemical processes in living organisms, contributing to the development of targeted therapies and interventions in medicine and biotechnology.

InChI:InChI=1/C3H6O2/c1-2-3(4)5/h2H2,1H3,(H,4,5)/i2D2/hD

Upstream product

• 516-05-2 methyl-propanedioic acid 
• 14770-50-4 methylmalonic acid-d3 
• 19136-91-5 (2,2-d₂)-propionic acid 
• 609-08-5 Diethyl methylmalonate 

Downstream Products

• 40422-14-8 2,2-dideuterio-propan-1-ol 

Relevant articles and documents

Deuterium and Carbon-13 NMR of the Solid Polymorphism of Benzenehexoyl Hexa-n-hexanoate

Deuterium and carbon-13 NMR of specifically labeled benzenehexoyl hexa-n-hexanoate in the various solid-state phases are reported.The spectra exhibit dynamic line shapes which change discontinuously at the phase transitions.The results are interpreted in terms of sequential "melting" of the side chains on going from the low-temperature solid phases IV, III, etc., toward the liquid.In phase IV the molecules are very nearly static, except for fast rotation of the methyl groups about their C3 axes.The results in phase III were quantitatively interpreted in terms of a two-site isomerization process ivolving simultaneous rotation by 95 deg about C1-C1 and transition from gtg to g'g't (or equivalently g'tg' to ggt) for the rest of the chain.The specific rate of this reaction at 0 deg C is ca. 1E5 s-1.In phase II additional chain isomerization processes set-in which were, however, not analyzed quantitatively.Further motional modes, involving reorintation of whole chains about their Car-O bonds, appear on going to phase I.In all solid phases the benzene ring remains static.

A McLafferty Rearrangement in an Even-electron System: C3H6 Elimination from the α-Cleavage Product of Tri-n-butylamine

It is shown by deuterium labelling, linked-scan measurements and collision activation that the .>+ (α-cleavage) ion in the electron impact ionization spectrum of tributylamine loses C3H6 with transfer of one hydrogen specifically from the γ-position.The experimental data point towards a mechanism which involves the intermediate formation of a distonic diradical ion from an excited α-cleavage ion which the eliminates the neutral alkene.

DEUTERATED LORCASERIN

This invention relates to novel compounds that are 3-benzazepine derivatives and pharmaceutically acceptable salts thereof. More specifically, this invention relates to novel 3-benzazepine derivatives that are derivatives of lorcaserin. This invention als