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147923-47-5

BOC-D-4,4-BIPHENYLALANINE, also known as Boc-D-4,4'-biphenylalanine, is an organic compound that serves as a crucial building block in the synthesis of various pharmaceutical compounds. It is characterized by its unique molecular structure, which features a biphenylalanine backbone protected by a tert-butyloxycarbonyl (Boc) group. This structure endows BOC-D-4,4-BIPHENYLALANINE with potential applications in the development of novel therapeutic agents.

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  • 147923-47-5 Structure

  • Basic information

    1. Product Name: BOC-D-4,4-BIPHENYLALANINE
    2. Synonyms: BOC-D-4,4'-BIPHENYLALANINE
    3. CAS NO:147923-47-5
    4. Molecular Formula: C20H23NO4
    5. Molecular Weight: 428.48
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 147923-47-5.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: -20°C Freezer
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. CAS DataBase Reference: BOC-D-4,4-BIPHENYLALANINE(CAS DataBase Reference)
    10. NIST Chemistry Reference: BOC-D-4,4-BIPHENYLALANINE(147923-47-5)
    11. EPA Substance Registry System: BOC-D-4,4-BIPHENYLALANINE(147923-47-5)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 147923-47-5(Hazardous Substances Data)

147923-47-5 Usage

Uses

Used in Pharmaceutical Industry:
BOC-D-4,4-BIPHENYLALANINE is used as a key intermediate in the synthesis of pyrrolopyrimidine inhibitors of Akt, which are considered as antitumor agents. These inhibitors target the Akt protein, a serine/threonine-specific protein kinase that plays a significant role in cell survival, growth, and angiogenesis. By inhibiting Akt, these compounds can potentially suppress tumor growth and progression.
BOC-D-4,4-BIPHENYLALANINE is also used in the preparation of (-)-Bestatin-based inhibitors. Bestatin, a naturally occurring aminoglycoside antibiotic, has been found to possess antitumor and immunomodulatory properties. The development of (-)-Bestatin-based inhibitors using BOC-D-4,4-BIPHENYLALANINE can lead to the creation of more potent and selective therapeutic agents for cancer treatment.

Check Digit Verification of cas no

The CAS Registry Mumber 147923-47-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,7,9,2 and 3 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 147923-47:
(8*1)+(7*4)+(6*7)+(5*9)+(4*2)+(3*3)+(2*4)+(1*7)=155
155 % 10 = 5
So 147923-47-5 is a valid CAS Registry Number.

147923-47-5Upstream product

147923-47-5Downstream Products

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