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Penicillin V β-Sulfoxide-d3 is a deuterated derivative of Penicillin V β-Sulfoxide, which is an intermediate in the synthesis of Penicillin V, a well-known antibacterial agent. Penicillin V β-Sulfoxide-d3 is characterized by the presence of deuterium (D) atoms, which are stable isotopes of hydrogen, replacing the hydrogen atoms in the molecule. This substitution can provide valuable insights into the compound's properties and behavior, making it a useful tool in various research and analytical applications.

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  • 148680-07-3 Structure
  • Basic information

    1. Product Name: Penicillin V β-Sulfoxide-d3
    2. Synonyms: Penicillin V β-Sulfoxide-d3;DNPOVSLJNLLGMA-AERZYDOTSA-N
    3. CAS NO:148680-07-3
    4. Molecular Formula: C16H18N2O6S
    5. Molecular Weight: 369.407405334
    6. EINECS: N/A
    7. Product Categories: Chiral Reagents, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals, Sulfur & Selenium Compounds
    8. Mol File: 148680-07-3.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: DMSO (Slightly), Methanol (Slightly)
    9. CAS DataBase Reference: Penicillin V β-Sulfoxide-d3(CAS DataBase Reference)
    10. NIST Chemistry Reference: Penicillin V β-Sulfoxide-d3(148680-07-3)
    11. EPA Substance Registry System: Penicillin V β-Sulfoxide-d3(148680-07-3)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 148680-07-3(Hazardous Substances Data)

148680-07-3 Usage

Uses

Used in Pharmaceutical Industry:
Penicillin V β-Sulfoxide-d3 is used as an intermediate in the synthesis of Penicillin V for its antibacterial properties. The deuterium labeling in this compound can help researchers study the metabolic pathways and pharmacokinetics of Penicillin V, leading to a better understanding of its mode of action and potential improvements in its therapeutic applications.
Used in Research and Development:
In the field of research and development, Penicillin V β-Sulfoxide-d3 can be employed as a labeled compound for various analytical techniques, such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. The presence of deuterium atoms can enhance the sensitivity and accuracy of these methods, allowing for more precise measurements and a deeper understanding of the compound's structure and interactions with other molecules.
Used in Drug Metabolism Studies:
Penicillin V β-Sulfoxide-d3 can be utilized in drug metabolism studies to investigate the metabolic fate of Penicillin V in the body. By tracking the deuterium-labeled compound, researchers can gain insights into the enzymes and pathways involved in the metabolism of Penicillin V, which can be crucial for optimizing its pharmacological properties and minimizing potential side effects.
Used in Drug Interaction Studies:
The deuterated derivative of Penicillin V β-Sulfoxide can also be employed in drug interaction studies to explore the potential for drug-drug interactions with Penicillin V. By monitoring the behavior of the deuterium-labeled compound in the presence of other drugs, researchers can identify possible competition for metabolic enzymes or transporters, which can help in the development of safer and more effective drug combinations.

Check Digit Verification of cas no

The CAS Registry Mumber 148680-07-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,8,6,8 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 148680-07:
(8*1)+(7*4)+(6*8)+(5*6)+(4*8)+(3*0)+(2*0)+(1*7)=153
153 % 10 = 3
So 148680-07-3 is a valid CAS Registry Number.

148680-07-3Relevant articles and documents

Syntheses of (2S,3S)-[4,4,4-2H3]- and (2S,3R)-[4,4,4-2H3]Penicillamine

Nanjappan,Ramalingam,Mosberg,Woodard

, p. 421 - 425 (2007/10/02)

(2S,3S)-[4,4,4-2H3]- and (2S,3R)-[4,4,4-2H3]Penicillamine (2-amino-3-mercapto-3-methyl-[4,4,4-2H3]butanoic acids) were synthesized from benzyl (1S,3S,6R)-6-(phenoxyacetylamino)penicillanate

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