148719-91-9

Basic information

• Product Name: 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S)
• Synonyms: 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S);4H-THIENO[2,3-B]THIOPYRAN-4-INE;(6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one 7,7-dioxide;(6S)-5,6-Dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one 7,
• CAS NO: 148719-91-9
• Molecular Formula: C₈H₈O₃S₂
• Molecular Weight: 216.28
• Mol File: 148719-91-9.mol

Chemical Properties

• Boiling Point: 441.861 °C at 760 mmHg
• Flash Point: 221.03 °C
• Appearance: /
• Density: 1.453
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.591
• CAS DataBase Reference: 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S)(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S)(148719-91-9)
• EPA Substance Registry System: 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S)(148719-91-9)

Safety Data

• Hazardous Substances Data: 148719-91-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S) is used as a pharmaceutical intermediate for the synthesis of various therapeutic agents. Its unique structure and properties may contribute to the development of new drugs with specific biological activities.
Used in Chemical Synthesis:
In the chemical industry, 4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S) serves as a key building block for the synthesis of more complex organic compounds. Its sulfur-containing and heterocyclic nature may enable the creation of novel molecules with diverse applications.
Used in Material Science:
4H-Thieno[2,3-b]thiopyran-4-one,5,6-dihydro-6-methyl-, 7,7-dioxide, (6S) may also find applications in material science, where its unique structural features could be leveraged to develop new materials with specific properties, such as improved stability or reactivity.

InChI:InChI=1/C8H8O3S2/c1-5-4-7(9)6-2-3-12-8(6)13(5,10)11/h2-3,5H,4H2,1H3/t5-/m0/s1

Upstream product

• 133359-80-5 (S)-3-(thien-2-ylthio)butyric acid 
• 147086-79-1 (S)-5,6-dihydro-6-methylthieno<2,3-b>thiopyran-4-one 

Downstream Products

• 1197375-13-5 (4S,6R)-4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran 7,7-dioxide 
• 147086-81-5 4H-thieno[2,3-b]thiopyran-4-ol-5,6-dihydro-6-methyl-7,7-dioxide 
• 147086-81-5 (4R,6S)-4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran 7,7-dioxide 

Relevant articles and documents

Process for obtaining 4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide and its enantiomers, and applications thereof

The invention relates to a process for obtaining cis-4-hydroxy-6-methyl-5,6-dihydro-4H-thieno[2,3-b]thiopyran-7,7-dioxide, its enantiomers or mixtures thereof, by reduction of 5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-4-one-7,7-dioxide with a reducing agent which generates hydride ions. The obtained compounds are useful as intermediates in the synthesis of chiral active ingredients.

ENZYMATIC ASYMMETRIC REDUCTION PROCESS TO PRODUCE 4 H-THIENO(2,3-6)THIO PYRANE DERIVATIVES

PCT No. PCT/GB93/01776 Sec. 371 Date Feb. 28, 1995 Sec. 102(e) Date Feb. 28, 1995 PCT Filed Aug. 20, 1993 PCT Pub. No. WO94/05802 PCT Pub. Date Mar. 17, 1994A compound of formula in which X is hydrogen or a group of formula -SO2NH2 is reduced to the trans (4S,6S) form of the corresponding alcohol by an enzyme reduction system.

β-Butyrolactone as a chiral building block in organic synthesis: A convenient synthesis of MK-0507 keto sulfone

The nucleophilic ring opening of (R)-β-butyrolactone 2 with 2-thiophenethiolate is the key step in a straightforward stereospecific synthesis of keto sulfone 1, a precursor to carbonic anhydrase inhibitor MK-0507.