Reductive amination of piperidines with aldehydes using borane-pyridine
Borane-pyridine complex (BAP) was found to be an excellent replacement for NaCNBH3 in the Borch reduction. Assorted aromatic, heterocyclic and aliphatic aldehydes were reacted with various substituted piperidines using standardized conditions.
Moormann
p. 789 - 795
(2007/10/02)
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