- NOVEL ANTIFUNGAL 5,6-DIHYDRO-4H-PYRROLO[1,2-a][1,4]- BENZODIAZEPINES AND 6H-PYRROLO[1,2-a][1,4]BENZODIAZEPINES SUBSTITUTED WITH BICYCLIC BENZENE DERIVATIVES
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The present invention is concerned with novel antifungal 5,6-dihydro-4H-pyrrolo- [1,2-a][1,4]benzodiazepines and 6H-pyrrolo[1,2-a][1,4]benzodiazepines substituted with bicyclic benzene derivatives of Formula (I) wherein R1, R2, Rsup
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Page/Page column 54
(2012/07/13)
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- Pyrrolo[1,2-a][1,4]benzodiazepine: A novel class of non-azole anti-dermatophyte anti-fungal agents
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Broad screening revealed compound 1a to be a novel anti-fungal agent with high specificity towards dermatophytes. The anti-fungal structure-activity relationship of this novel class of 5,6-dihydro-4H-pyrrolo[1,2-a][1,4] benzodiazepines is described togeth
- Meerpoel, Lieven,Van Gestel, Jef,Van Gerven, Frans,Woestenborghs, Filip,Marichal, Patrick,Sipido, Vic,Terence, Gilkerson,Nash, Roger,Corens, David,Richards, Ray D.
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p. 3453 - 3458
(2007/10/03)
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