14922-91-9

Basic information

• Product Name: 5-Bromo-2-ethyl-phenylamine
• Synonyms: 5-Bromo-2-ethyl-phenylamine;5-bromo-2-ethylbenzenamine;5-Bromo-2-ethylaniline
• CAS NO: 14922-91-9
• Molecular Formula: C₈H₁₀BrN
• Molecular Weight: 200.0757
• Mol File: 14922-91-9.mol

Chemical Properties

• Boiling Point: 275.3±20.0 °C(Predicted)
• Appearance: /
• Density: 1.421±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 3.29±0.10(Predicted)
• CAS DataBase Reference: 5-Bromo-2-ethyl-phenylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-ethyl-phenylamine(14922-91-9)
• EPA Substance Registry System: 5-Bromo-2-ethyl-phenylamine(14922-91-9)

Safety Data

• Hazardous Substances Data: 14922-91-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Bromo-2-ethyl-phenylamine is used as a building block for the synthesis of various pharmaceuticals due to its unique structure and reactivity. It contributes to the development of new drugs by providing a versatile starting material for chemical reactions in medicinal chemistry.
Used in Dye Industry:
In the dye industry, 5-Bromo-2-ethyl-phenylamine is utilized as a precursor in the production of dyes. Its aromatic amine structure allows for the creation of dyes with specific color properties and stability.
Used in Organic Synthesis:
5-Bromo-2-ethyl-phenylamine is employed as a key intermediate in organic synthesis for the preparation of a wide range of organic compounds. Its bromine atom and ethyl group enable various chemical reactions, making it a useful component in the synthesis of complex organic molecules.
Used in Research and Development:
5-Bromo-2-ethyl-phenylamine is used as a research compound in academic and industrial laboratories. Its unique properties make it an interesting subject for studies in chemical reactions, medicinal chemistry, and the development of new synthetic methods.
Used in Chemical Education:
In educational settings, 5-Bromo-2-ethyl-phenylamine can be used as a teaching aid to demonstrate the properties and reactions of aromatic amines, as well as the importance of safety precautions in handling reactive chemicals.

Upstream product

• 589-16-2 4-aminoethylbenzene 
• 51529-96-5 4-ethyl-3-nitroaniline 
• 612-22-6 2-nitro(ethylbenzene) 
• 10342-66-2 4-bromo-1-ethyl-2-nitro-benzene 

Downstream Products

• 1033760-94-9 4-bromo-1-ethyl-2-iodobenzene 
• 1033760-95-0 5-bromo-2-ethylphenylboronic acid 
• 1033760-96-1 5-bromo-2-ethylphenyllead triacetate 
• 1068111-07-8 9-(5-(4'-chlorophenyl)-2-ethylphenyl)-3-oxaspiro[5.5]undecane-8,10-dione 
• 1090512-25-6 C₁₆H₁₇BrO₂ 
• 1090512-29-0 C₁₇H₁₉BrO₂ 
• 1090512-26-7 C₁₆H₁₇IO₂ 
• 1090512-27-8 C₁₆H₁₉BO₄ 
• 1090511-11-7 C₁₉H₁₉ClN₂O₂ 
• 1090511-10-6 C₁₉H₁₉ClN₂O₂ 
• 1090511-08-2 C₂₁H₂₁NO₃ 
• 1090511-07-1 C₂₀H₂₁NO₂S 
• 1090511-06-0 C₂₁H₂₀ClNO₂ 
• 1090511-13-9 C₂₃H₂₃ClO₂ 

Relevant articles and documents

Preparation method of pazopanib intermediate

The invention provides a preparation method of a pazopanib key intermediate 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method comprises the following steps: by taking 6-halogenated-2,3-dimethyl-2H-indazole as a raw material, conducting reacting to obtain N,2,3-trimethyl-2H-indazole-6-amine; and further carrying out a reaction to obtain the 2,3-dimethyl-N-(2-chloropyrimidin-4-yl)-N-methyl-2H-indazole-6-amine. The method has the advantages of short synthesis route, accessible raw materials, low cost, mild reaction conditions, high safety and high yield, and is suitable for industrial mass production.

NOVEL HERBICIDES

Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides.

NOVEL HERBICIDES

Compounds of formula (I) wherein the substituents are as defined in claim 1, are suitable for use as herbicides.

NOVEL HERBICIDES

Cyclohexanedione compounds, which are suitable for use as herbicides.

NOVEL HERBICIDES

Pyrandione, thiopyrandione and cyclohexanetrione derivatives of formula (I), which are suitable for use as herbicides.

NOVEL HERBICIDES

Pyranone, thiopyranone and cyclohexenedione compounds of formula (I), which are suitable for use as herbicides.

2-ARYL-5-HETEROCYCLYL-CYCLOHEXANE-1,3-DIONE COMPOUNDS AND THEIR USE AS HERBICIDES

Cyclohexanedione compounds of Formula (I) wherein R1 is methyl, ethyl, n-propyl, iso-propyl, cyclopropyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, R2 and R3 are, independently hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C6alkoxy, C1-C6haloalkoxy, C2-C6alkenyl, C2-C6haloalkenyl, C2-C6alkynyl, C3-C6alkenyloxy, C3-C6haloalkenyloxy, C3-C6alkynyloxy, C3-C6cycloalkyl, C1-C6alkylthio, C1-C6alkylsulfinyl, C1-C6alkylsulfonyl, C1-C6alkylsulfonyloxy, C1-C6haloalkylsulfonyloxy, cyano, nitro, phenyl, phenyl substituted by C1-C4alkyl, C1-C3Cahaloalkyl, C1-C3alkoxy, C1-C3haloalkoxy, cyano, nitro, halogen, C1-C3alkylthio, C1-C3alkylsulfιnyl or C1-C3alkylsulfonyl, or heteroaryl or heteroaryl substituted by C1-C3Calkyl, d.Cahaloalkyl, C1-C3aIkoxy, C1-C3haloalkoxy, cyano, nitro, halogen, C1-C3alkylthio, C1-C3alkylsulfinyl or C1-C3alkylsulfonyl, R4 is hydrogen, methyl, ethyl, n-propyl, iso-propyl, halomethyl, haloethyl, halogen, vinyl, ethynyl, methoxy, ethoxy, halomethoxy or haloethoxy, X is O, S, S(O) or S(O)2, R5 is hydrogen or methyl, R6 is hydrogen, methyl or ethyl, or forms a double bond, which links the carbon atom, to which R6is attached, with the adjacent carbon atom of R7 or R8, R7 and R8 are independently of each other C1-C5alkylene, which is unsubstituted or substituted by methyl or ethyl, or C2-C5alkenylene, which is unsubstituted or substituted by methyl or ethyl, and G is hydrogen, an alkali metal, alkaline earth metal, sulfoniυm, ammonium or a latentiating group, are suitable for use as herbicides.

NOVEL HERBICIDES

Cyclohexanedione compounds, and derivatives thereof, which are substituted in 5-position, are suitable for use as herbicides.

HERBICIDALLY ACTIVE BICYCLIC 1,3-DIONE COMPOUNDS

Bicyclic dione compounds of formule (I), and derivatives thereof, which are suitable for use as herbicides.

4-PHENYL-PYRANE-3,5-DIONES, 4-PHENYL-THIOPYRANE-3,5-DIONES AND CYCLOHEXANETRIONES AS NOVEL HERBICIDES

Pyrandione, thiopyrandione and cyclohexanetrione compounds, which are suitable for use as herbicides.