This invention provides compounds having drug and bio-affecting properties, their pharmaceutical compositions and method of use. In particular, the invention is concerned with amido piperazine derivatives. These compounds possess unique antiviral activity
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Page/Page column 31
(2008/06/13)
Some new quinoline-based mono and dicarboxylic acids
Some quinoline-based mono- and dicarboxylic acids structurally related to kynurenic acid have been synthesized and screened as antagonists of neurotransmission of NMDA, AMPA and KA excitatory amino acid receptors. Higher affinity for NMDA receptor was pointed out in the short series, but all the compounds, even those with key structural features of glutamic acid showed no significant activity.
Ferranti,Garuti,Giovanninetti,Roberti,Varoli
p. 1547 - 1553
(2007/10/02)
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