- Synthesis of Malonaldehyde Monoacetals
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The synthesis of a series of malonaldehyde manoacetals is described.Selective hydrolysis or transacetalisation of 1,1,3,3-tetramethoxypropane and its analogues was proved to be a very general technique.
- Shi-Qi, Peng,Winterfeldt, Ekkehard
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p. 1045 - 1047
(2007/10/02)
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- Chemistry of the podocarpaceae LXXI. Preparation, structure, and reactions of some (arene)tricarbonylchromium(0) complexes. Crystal structure of α-tricarbonylchromium(0)
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Tricarbonylchromium(0) (7), tricarbonylchromium(0) (11) and (benzene)tricarbonylchromium(0) (10) were prepared and examined.Complex 7 was obtained as a mixture of diastereomers, an X-ray structural determination showing that the α-isomer possesses a near eclipsed conformation, in agreement with the conformation in solution deduced from 400 MHz 1H NMR analysis.Carbanions derived from 1,3-dithiane, 2-methyl-1,3-dithiane and 2-(2,2-dimethoxyethyl)-1,3-dithiane (24), and the dianion derived from 2,2'-methylenebis-1,3-dithiane (27) were prepared and brought into reaction with the complexes.Compounds 23 and 33 resulted from regioselective attack on 7 at the site predicted.Treatment with methyl electrophiles of the dithianyl η5-intermediate leading to 22 did not give products of acetyl incorporation.Arene lithiation-electrophilic quenching of 7 gave a mixture of compound 6 and its C(14) regioisomer along with the novel ketone 39 and its C(14) regioisomer.
- Cambie, Richard C.,Clark, George R.,Gallagher, Stewart R.,Rutledge, Peter S.,Stone, Martin J.,Woodgate, Paul D.
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p. 315 - 338
(2007/10/02)
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