149809-34-7

Basic information

• Product Name: 1-2-(2,4-difluorophenyl)-2-propenol acetate
• Synonyms: 1-2-(2,4-difluorophenyl)-2-propenol acetate;2-(2,4-Difluorophenyl)-2-propenyl acetate;2-(2,4-Difluorophenyl)-2-propenol acetate;2-(2,4-difluorophenyl)prop-2-en-1-yl acetate;2-(2,4-Difluorophenyl)allyl acetate
• CAS NO: 149809-34-7
• Molecular Formula: C₁₁H₁₀F₂O₂
• Molecular Weight: 212.19
• Mol File: 149809-34-7.mol

Chemical Properties

• Boiling Point: 264.5±30.0 °C(Predicted)
• Appearance: /
• Density: 1.177±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-2-(2,4-difluorophenyl)-2-propenol acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-2-(2,4-difluorophenyl)-2-propenol acetate(149809-34-7)
• EPA Substance Registry System: 1-2-(2,4-difluorophenyl)-2-propenol acetate(149809-34-7)

Safety Data

• Hazardous Substances Data: 149809-34-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1-2-(2,4-difluorophenyl)-2-propenol acetate is used as a reagent and intermediate for the synthesis of pharmaceutical compounds due to its reactivity and the ability to form a variety of chemical bonds, contributing to the creation of new drug molecules with potential therapeutic applications.
Used in Flavor and Fragrance Industry:
1-2-(2,4-difluorophenyl)-2-propenol acetate is used as a key component in the production of flavors and fragrances, capitalizing on its faint floral odor to enhance or create unique scents and tastes in various consumer products.
Used in Organic Synthesis:
1-2-(2,4-difluorophenyl)-2-propenol acetate is utilized as a versatile intermediate in organic synthesis, allowing for the development of a wide range of chemical products, from specialty chemicals to advanced materials, due to its capacity to participate in multiple types of chemical reactions.

Downstream Products

• 141113-36-2 2-(2,4-difluorophenyl)allyl alcohol 

Relevant articles and documents

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two amino acid ester groups (e.g., an amino acid ester group convertible in vivo into a hydroxy group) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two groups convertible in vivo into hydroxy moieties, (e.g., a polyether ester, amino acid ester or phosphate ester) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy moieties, an ether or ester thereof (e.g., a polyether ester amino acid ester or phosphate ester) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two phosphate ester groups (e.g., a phosphate ester convertible in vivo into a hydroxy group) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tetrahydrofuran antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two polyetyher ester groups (e.g., a polyether ester convertible in vivo into a hydroxy group) thereof or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Hydroxy-substituted antifungals

A compound represented by the formula I STR1 wherein X is independently both F or both Cl or one X is independently F and the other is independently Cl; R1 is a straight or branched chain (C3 to C8) alkyl group substituted by one or two hydroxy moieties, an ether or ester thereof (e.g., a polyether ester, heterocyclic ester amino acid ester or phosphate ester) thereof and the carbon with the asterisk (*) has the R or S absolute configuration or a pharmaceutically acceptable salt thereof and pharmaceutical compositions thereof useful for treating and/or preventing fungal infections are disclosed.

Tri-substituted tetrahydrofuran antifungals

An antifungal compound represented by formula [I]: wherein X is independently both F or both Cl or one X is F and the other is Cl; Y=R'= (C1-C10) alkyl; (C2-C10)alkenyl; (C2-C10)alkynyl; (C3-C8)cycloalky or CH2R2; R2= (C1-C3)perhaloalkyl; CO2R3 *CH(OR4)CH2OR4 or CH2N(R5) R3= lower alkyl or H R4= R3 or (CH2)2OR3 R5= lower alkyl Z=H, or (C1-C5) alkanoyl and the carbons with the asterisks (*) have the R or S absolute configuration; or a pharmaceutically acceptable salt thereof as well as pharmacetical compositions containing them and a methods of treating or preventing fungal infections in mammals using them are disclosed.