149811-53-0

Basic information

• Product Name: Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, cis- (9CI)
• Synonyms: Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, cis- (9CI);(1R,2R)-1-amino-2-isopropyl-cyclopropanecarboxylic acid
• CAS NO: 149811-53-0
• Molecular Formula: C7H13NO2
• Molecular Weight: 143.18362
• Product Categories: AMINOACID
• Mol File: 149811-53-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, cis- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, cis- (9CI)(149811-53-0)
• EPA Substance Registry System: Cyclopropanecarboxylic acid, 1-amino-2-(1-methylethyl)-, cis- (9CI)(149811-53-0)

Safety Data

• Hazardous Substances Data: 149811-53-0(Hazardous Substances Data)

Upstream product

• 123311-14-8 p-nitrobenzyl 3-<(benzyloxycarbonyl)amino>-5-isopropyl-1-pyrazoline-3-carboxylate 
• 123311-16-0 N-(benzyloxycarbonyl)-(Z)-2,3-methanoleucine p-nitrobenzyl ester 
• 123311-17-1 N-(benzyloxycarbonyl)-(E)-2,3-methanoleucine p-nitrobenzyl ester 

Relevant articles and documents

1-Aminocyclopropane-1-carboxylic acid derivatives: A new, general synthesis and NMDA receptor complex binding affinity study

A new synthesis of 1-aminocyclopropane-1-carboxylic acid and of its (E)- and (Z)-2-substituted analogues (R = CH3;i-Pr;C6H5) has been performed by means of the 'diazo-addition' method, starting from N-(diphenylmethylene)-2,3-dehydro-1-amino-1-carboxylate precursors. The (E)- and (Z)-2-phenyl and the (Z)-2-methylcyclopropaneamino acids have been obtained with high diastereospecificity. All the cyclopropaneamino acids prepared were tested for their affinity for some glutamate receptors and resulted inactive, wich the exception of compounds (E)-1b and (Z)-1c which showed a shallow displacement of [H]-glycine binding.