149817-31-2

Basic information

• Product Name: 2-(3,5-DIMETHYLBENZOYL)BENZOIC ACID
• Synonyms: 2-(3,5-DIMETHYLBENZOYL)BENZOIC ACID
• CAS NO: 149817-31-2
• Molecular Formula: C₁₆H₁₄O₃
• Molecular Weight: 254.28
• Mol File: 149817-31-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(3,5-DIMETHYLBENZOYL)BENZOIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-DIMETHYLBENZOYL)BENZOIC ACID(149817-31-2)
• EPA Substance Registry System: 2-(3,5-DIMETHYLBENZOYL)BENZOIC ACID(149817-31-2)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 149817-31-2(Hazardous Substances Data)

Usage

Chemical Class

2-(3,5-dimethylbenzoyl)benzoic acid belongs to the class of benzoylbenzoic acids.

Physical Appearance

The compound is a white crystalline solid.

Solubility

It is sparingly soluble in water but more soluble in organic solvents such as ethanol and ether.

Chemical Structure

The structure consists of a benzoyl group attached to a benzoic acid group, with two methyl groups located on the benzene ring.

Versatile Chemical Properties

2-(3,5-dimethylbenzoyl)benzoic acid has versatile chemical properties, making it commonly used in the synthesis of various pharmaceuticals and organic molecules.

Building Block

The compound is a valuable building block in the field of organic chemistry.

Applications

2-(3,5-dimethylbenzoyl)benzoic acid has various applications in the production of drugs, dyes, and other organic compounds.

Upstream product

• 85-44-9 phthalic anhydride 
• 34696-73-6 3,5-dimethyphenylmagnesium bromide 
• 556-96-7 5-bromo-1,3-xylene 

Downstream Products

• 143390-74-3 (R)-9b-(3,5-Dimethyl-phenyl)-2,3-dihydro-9bH-thiazolo[2,3-a]isoindol-5-one 
• 143390-74-3 9b-(3,5-dimethylphenyl)2,3-dihydrothiazolo[2,3-a]-isoindol-5(9bH)-one 
• 856352-55-1 2-(3,5-dimethyl-benzyl)-benzoic acid 

Relevant articles and documents

Decarboxylative C-H arylation of benzoic acids under radical conditions

A decarboxylative radical cyclization reaction has been developed for the synthesis of fluorenones. The reaction uses Ag(I)/K2S 2O8 to oxidatively decarboxylate an aroylbenzoic acid to an aryl radical, which undergoes cyclization to afford fluorenone products in good yield.

Study of intramolecular hydrogen abstraction on photoexcited 1,3-dimethylanthrone in the condensed phase

The time-resolved thermal lensing (TRTL) technique was applied to determine the reaction heat of intramolecular hydrogen abstraction for excited 1,3-dimethylanthrone (DMAT). The excited carbonyl group abstracts the hydrogen atom of the neighboring methyl group to produce an intermediate. The intermediate decayed with 1.2±0.1 μs. The heat conversion efficiency was determined to be 1.02±0.02, revealing that excited DMAT emits all the energy as heat. The time profile of a TRTL signal led to the value of the reaction heat for the intermediate, 131±6 kJ/mol. We briefly discuss candidates for the intermediate.