14994-16-2

Basic information

• Product Name: 2-CHLORO-5-FLUORO-1,3-DIMETHYLBENZENE
• Synonyms: 2-CHLORO-5-FLUORO-1,3-DIMETHYLBENZENE;2-Chloro-5-fluoro-1,3-dimethylbenzene 98%;2-Chloro-5-fluoro-1,3-dimethylbenzene98%;2,6-Dimethyl-4-fluorochlorobenzene 98%;2-Chloro-1,3-dimethyl-5-fluorobenzene, 2-Chloro-5-fluoro-m-xylene;2,6-Dimethyl-4-fluorochlorobenzene98%
• CAS NO: 14994-16-2
• Molecular Formula: C₈H₈ClF
• Molecular Weight: 158.6
• Mol File: 14994-16-2.mol

Chemical Properties

• Boiling Point: 186.9°Cat760mmHg
• Flash Point: 73.4°C
• Appearance: /
• Density: 1.148g/cm³
• Vapor Pressure: 0.89mmHg at 25°C
• Refractive Index: 1.502
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-CHLORO-5-FLUORO-1,3-DIMETHYLBENZENE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5-FLUORO-1,3-DIMETHYLBENZENE(14994-16-2)
• EPA Substance Registry System: 2-CHLORO-5-FLUORO-1,3-DIMETHYLBENZENE(14994-16-2)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36/37/39
• Hazardous Substances Data: 14994-16-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-fluoro-1,3-dimethylbenzene is utilized as an intermediate in the synthesis of various pharmaceuticals. Its unique chemical structure allows for the development of new drugs with specific therapeutic properties, contributing to the advancement of medicinal chemistry.
Used in Pesticide Industry:
In the agricultural sector, 2-chloro-5-fluoro-1,3-dimethylbenzene serves as a key intermediate in the production of certain pesticides. Its incorporation into these compounds aids in the creation of effective pest control agents, enhancing crop protection and contributing to increased agricultural productivity.
Used in Organic Compounds Synthesis:
Beyond its applications in pharmaceuticals and pesticides, 2-chloro-5-fluoro-1,3-dimethylbenzene is also employed as an intermediate in the synthesis of other organic compounds. Its versatile chemical structure makes it a valuable building block in organic chemistry, facilitating the creation of a wide range of specialty chemicals for various industrial applications.

InChI:InChI=1/C8H8ClF/c1-5-3-7(10)4-6(2)8(5)9/h3-4H,1-2H3

Upstream product

• 392-70-1 2,6-dimethyl-4-fluoroaniline 
• 3095-38-3 3,5-dimethyl-4-nitrobenzoic acid 
• 315-12-8 2,6-dimethyl-4-fluoro-1-nitro-benzene 
• 34761-82-5 3,5-dimethyl-4-nitroaniline 
• 19023-45-1 3,5-dimethyl-4-nitro-benzoic acid amide 
• 461-97-2 3,5-dimethylfluorobenzene 
• 88-04-0 4-Chloro-3,5-dimethylphenol 
• 1242759-17-6 4-chloro-3,5-dimethylphenyl trifluoromethanesulfonate 
• 214774-61-5 2,4-dichloro-5-fluoro-1,3-dimethylbenzene 

Relevant articles and documents

An improved catalyst system for the Pd-catalyzed fluorination of (hetero)aryl triflates

The stable Pd(0) species [(1,5-cyclooctadiene)(L·Pd)2] (L = AdBrettPhos) has been prepared and successfully evaluated as a precatalyst for the fluorination of aryl triflates derived from biologically active and heteroaryl phenols, challenging substrates for our previously reported catalyst system. Additionally, this precatalyst activates at room temperature under neutral conditions, generates 1,5-cyclooctadiene as the only byproduct, and leads to overall cleaner reaction profiles.

Use of 7-(1-aminomethyl-2-oxa-7-aza-bicyclo[3.3.0]oct-7-yl)-quinolone carboxylic acid and naphthyridone carboxylic acid derivatives for treating Helicobacter pylori infections and the gastroduodenal diseases associated therewith

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3-cyano-2,4,5-trifluoro-benzoyl fluoride and intermediate products for the production thereof

The present invention relates to 3-cyano-2,4,5-trifluorobenzoyl fluoride and to intermediates for its preparation and to the process for the preparation of 3-cyano-2,4,5-trifluoro-benzoyl fluoride, which starts from 5 fluoro-1,3-xylene (VIII); which is bi

Use of 7-(2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-quinolone carboxylic acid and naphthyridon carboxylic acid derivatives for the treatment of Helicobacter pylori infections and associated gastroduodenal diseases

PCT No. PCT/EP97/06781 Sec. 371 Date Jun. 14, 1999 Sec. 102(e) Date Jun. 14, 1999 PCT Filed Dec. 4, 1997 PCT Pub. No. WO98/26779 PCT Pub. Date Jun. 25, 1998The invention relates to the use of quinolone- and naphthyridonecarboxylic acid derivatives which a