Design, synthesis, antimicrobial, and DNA gyrase inhibitory properties of fluoroquinolone–dichloroacetic acid hybrids
A series of new fluoroquinolone conjugates 8a–g and 9a–f were synthesized via benzotriazole-mediated synthetic approach with good yield and purity. Some of the synthesized analogs exhibited significant antibacterial properties against Escherichia coli and
Seliem, Israa A.,Panda, Siva S.,Girgis, Adel S.,Nagy, Yosra I.,George, Riham F.,Fayad, Walid,Fawzy, Nehmedo G.,Ibrahim, Tarek S.,Al-Mahmoudy, Amany M. M.,Sakhuja, Rajeev,Abdel-samii, Zakaria K. M.