151221-98-6Relevant articles and documents
Stilbene derivatives as anticancer agents
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, (2008/06/13)
The present invention relates to stilbene derivatives which possess utility as anti-cancer agents. The compounds can be used to treat cancers which are susceptible to treatment therewith, and can be utilized in a method of treating such cancers. Pharmaceu
Synthesis and Evaluation of a Series of Benzylaniline Hydrochlorides as Potential Cytotoxic and Antimitotic Agents Acting by Inhibition of Tubulin Polymerization
Cushman, Mark,He, Hu-Ming,Lin, Chii M.,Hamel, Ernest
, p. 2817 - 2821 (2007/10/02)
Although certain substituted cis-stilbenes have displayed potent tubulin polymerization inhibitory activity and significant cytotoxicities in cancer cell cultures, these compounds have limited aqueous solubility and are therefore difficult to formulate fo