Indole chalcones: Design, synthesis, in vitro and in silico evaluation against Mycobacterium tuberculosis
Indole chalcones were designed and synthesized as a promising set of compounds against H37Rv strain of Mycobacterium tuberculosis. Within this library of compounds, (E)-1-(furan-3-yl)-3-(1H-indol-3-yl)prop-2-en-1-one (18), (E)-3-(1H-indol-3-yl)
Anti-inflammatory, analgesic and antipyretic 4,6-disubstituted 3-cyano- 2-aminopyridines
4,6-diaryl and 4,6-aryl-indolyl substituted 3-cyano-2-aminopyridines were synthesized and submitted to evaluation for their anti-inflammatory, analgesic and antipyretic activity. The electronegativity of the substituents and their displacement on the 4- o
Manna, Fedele,Chimenti, Franco,Bolasco, Adriana,Bizzarri, Bruna,Filippelli, Walter,Filippelli, Amelia,Gagliardi, Luigi
p. 245 - 254
(2007/10/03)
Research of antiparasitic agents: 1-(nitrophenyl)3-methyl-3-indolyl)-prop-2-ene-1-ones (nitroindolylchalcones
The synthesis and the study of the antiparasitic properties of various 1-(nitrophenyl)-3-(methyl-3-indolyl)-prop-2-ene-1-ones (Nitroindolylchalcones) show interesting antiprotozoal activities on E. histolytica and T. vaginalis. No significant activity app
Alaoui,Gayral,Kirkiacharian
p. 260 - 265
(2007/10/02)
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