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(1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol, also known as intermedine, is a pyrrolizidine alkaloid with the molecular formula C7H13NO2. It is found in several plant species, including members of the Senecio and Crotalaria genera. This chemical compound features an epoxy group and a hydroxyl group in its structure, which contribute to its biological activity and potential toxicity. Due to its liver toxicity, intermedine and other pyrrolizidine alkaloids are of concern in food safety and herbal medicine.

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  • 15211-03-7 Structure
  • Basic information

    1. Product Name: (1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol
    2. Synonyms: (1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol;1,2β-Epoxytrachelanthamidine;1,2-Epoxy-1-hydroxymethylpyrrolizidine
    3. CAS NO:15211-03-7
    4. Molecular Formula: C8H13NO2
    5. Molecular Weight: 155.19432
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 15211-03-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol(CAS DataBase Reference)
    10. NIST Chemistry Reference: (1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol(15211-03-7)
    11. EPA Substance Registry System: (1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol(15211-03-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15211-03-7(Hazardous Substances Data)

15211-03-7 Usage

Uses

Used in Pharmaceutical Research:
(1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol is used as a subject of pharmaceutical research for its potential biological activity. Despite its toxicity, understanding its mechanism of action can aid in the development of drugs targeting specific biological pathways or in the creation of detoxification methods for pyrrolizidine alkaloid poisoning.
Used in Toxicological Studies:
Intermedine is utilized in toxicological studies to investigate the effects of pyrrolizidine alkaloids on liver function and overall health. This research is crucial for establishing safety guidelines and regulations to prevent exposure to these toxic compounds through food or herbal remedies.
Used in Food Safety and Herbal Medicine Regulation:
(1S,2β,7aα)-1,2-Epoxyhexahydro-1H-pyrrolizine-1-methanol serves as a reference compound in the development of testing methods and regulations for food safety and herbal medicine. Monitoring the presence of intermedine and related alkaloids in these products helps protect consumers from potential health risks associated with their consumption.

Check Digit Verification of cas no

The CAS Registry Mumber 15211-03-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,2,1 and 1 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 15211-03:
(7*1)+(6*5)+(5*2)+(4*1)+(3*1)+(2*0)+(1*3)=57
57 % 10 = 7
So 15211-03-7 is a valid CAS Registry Number.

15211-03-7Upstream product

15211-03-7Downstream Products

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