Welcome to LookChem.com Sign In|Join Free

CAS

  • or

152449-64-4

(2Z)-5-[(4-chlorophenyl)amino]methyl-2-imino-3-[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino-1,3-thiazolidin-4-one, also known as Cilastatin, is a potent antibiotic drug with a complex chemical structure that includes a thiazolidine-4-one ring, an imino group, a chlorophenyl group, and a phenylmethylidene group. It is commonly used in combination with Imipenem to treat severe infections.

152449-64-4 Suppliers

Post Buying Request

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier
  • 152449-64-4 Structure

  • Basic information

    1. Product Name: (2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one
    2. Synonyms:
    3. CAS NO:152449-64-4
    4. Molecular Formula: C24H21ClN6O2S
    5. Molecular Weight: 492.9805
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 152449-64-4.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 656.097°C at 760 mmHg
    3. Flash Point: 350.595°C
    4. Appearance: N/A
    5. Density: 1.379g/cm3
    6. Vapor Pressure: 0mmHg at 25°C
    7. Refractive Index: 1.682
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: (2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one(CAS DataBase Reference)
    11. NIST Chemistry Reference: (2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one(152449-64-4)
    12. EPA Substance Registry System: (2Z)-5-{[(4-chlorophenyl)amino]methyl}-2-imino-3-{[(Z)-[(E)-(4-methoxyphenyl)diazenyl](phenyl)methylidene]amino}-1,3-thiazolidin-4-one(152449-64-4)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 152449-64-4(Hazardous Substances Data)

152449-64-4 Usage

Uses

Used in Pharmaceutical Industry:
Cilastatin is used as a renal dehydropeptidase inhibitor for enhancing the effectiveness of Imipenem, a broad-spectrum antibiotic. By inhibiting the enzyme that would otherwise break down Imipenem, Cilastatin allows the antibiotic to remain active in the body for longer periods, thereby improving its efficacy in treating bacterial infections.
Used in Treatment of Severe Infections:
Cilastatin is used in combination with Imipenem to treat a variety of severe infections, particularly those caused by multi-drug resistant bacteria. This combination therapy helps in managing infections that are difficult to treat with standard antibiotics alone.
Used in Hospital Settings:
Cilastatin, in conjunction with Imipenem, is used in hospitals and other healthcare settings to provide effective treatment for patients with serious bacterial infections, including those acquired in healthcare environments or resistant to multiple antibiotics.

Check Digit Verification of cas no

The CAS Registry Mumber 152449-64-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,2,4,4 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 152449-64:
(8*1)+(7*5)+(6*2)+(5*4)+(4*4)+(3*9)+(2*6)+(1*4)=134
134 % 10 = 4
So 152449-64-4 is a valid CAS Registry Number.

152449-64-4Downstream Products

152449-64-4Relevant articles and documents

Thiazolidinone congeners as central nervous system active agents

Tripathi,Verma,Gujrati,Palit,Shanker

, p. 632 - 635 (2007/10/02)

3-(Benzylidene amino)-2-imino-4-thiazolidinones (IIa-c) synthesized by cyclization of substituted thiosemicarbazones (Ia-c) were converted into 2-amino-3-(substited benzylamino)-4-thiazolidinones (IIIa-c), 2-imino-3-(α-aryl azo benzylidene) amino-4-thiazo

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 152449-64-4