- Synthesis and anti-influenza virus activity of tricyclic compounds with a unique amine moiety
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Several novel tricyclic compounds with a unique amine moiety (1, 2a - i) were designed and prepared based on the structure of triperiden for the development of anti-influenza virus agents. An in vitro antiviral assay showed that 1-(1-azabicyclo[3.3.)]octa
- Oka,Ishiwata,Iwata,Honda,Kakigami
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- Antivirally active N-cycloalkyl alkanol compounds
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The compounds are of the general formula or where R1 is -OH, amino or -SH, R2 is H, α- or β-naphthyl or optionally substituted phenyl, R3 is mono-, di- or tricycloalkyl of C6-16, optionally substituted, R4
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