152536-17-9

Basic information

• Product Name: 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester
• Synonyms: 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester;methyl 4-chloroquinazoline-6-carboxylate;Methyl 4-chloroquinazolin...;4-chloroquinazoline-6-carboxylic acid
• CAS NO: 152536-17-9
• Molecular Formula: C₁₀H₇ClN₂O₂
• Molecular Weight: 222.62778
• Product Categories: CHIRAL CHEMICALS
• Mol File: 152536-17-9.mol

Chemical Properties

• Boiling Point: 355.5 °C at 760 mmHg
• Flash Point: 168.8 °C
• Appearance: /
• Density: 1.392 g/cm³
• Vapor Pressure: 3.11E-05mmHg at 25°C
• Refractive Index: 1.631
• PKA: 0.11±0.30(Predicted)
• CAS DataBase Reference: 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester(152536-17-9)
• EPA Substance Registry System: 6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester(152536-17-9)

Safety Data

• Hazardous Substances Data: 152536-17-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester is used as a key intermediate in the synthesis of various pharmaceutical drugs. Its unique structure and functional groups enable the development of new therapeutic agents with potential applications in treating cancer and neurological disorders.
Used in Agrochemical Industry:
6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester is used as a building block in the production of agrochemicals, such as pesticides and herbicides. Its ability to modulate biological pathways makes it a promising candidate for the development of novel agrochemicals with improved efficacy and selectivity.
Used in Organic Synthesis:
6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester is used as a valuable building block in organic synthesis. Its chlorine substituent provides an opportunity for further functionalization, allowing the synthesis of a wide range of organic compounds with diverse applications in various industries.
Used in Research and Development:
6-Quinazolinecarboxylic acid, 4-chloro-, methyl ester is used in research and development for the exploration of its potential applications in various fields, such as drug discovery, agrochemical development, and organic synthesis. Its unique structure and functional groups make it an interesting target for scientific investigation and innovation.

InChI:InChI=1/C10H7ClN2O2/c1-15-10(14)6-2-3-8-7(4-6)9(11)13-5-12-8/h2-5H,1H3

Upstream product

• 152536-21-5 4-oxo-3,4-dihydro-quinazoline-6-carboxylic acid methyl ester 

Downstream Products

• 648449-06-3 4-chloro-quinzoline-6-yl methanol 

Relevant articles and documents

2-IMINO-4-(THIO) OXO-5-POLY CYCLOVINYLAZOLINES FOR USE AS P13 KINASE IHIBITORS

The present invention is related to 2-imino-azolinone-vinyl fused-benzene derivatives of Formula (1) in particular for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, kidney diseases, platelet aggregation, cancer, transplantation, graft rejection or lung injuries.

AZOLIDINONE-VINYL FUSED-BENZENE DERIVATIVES

The present invention is related to azolidinedione-vinyl fused-benzene derivatives of formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, graft rejection or lung injuries. Formula (I), wherein A, X, Y, Z, R1 , R2 and n are as described in the description.