cas 153390-61-5, 1-(3-TrifluoroMethylphenyl)-1-MethylethylaMine | Articles data ｜lookchem

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153390-61-5

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Substituted Arylimidazolone and Triazolone as Inhibitors of Vasopressin Receptors
The present application relates to novel, substituted 4-arylimidazol-2-ones and 5-aryl-1,2,4-triazolones, processes for the production thereof, the use thereof alone or in combinations for the treatment and/or prevention of diseases and the use thereof for the production of medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular diseases.
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Page/Page column 19

(2009/12/27)

HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE
The present invention relates to novel hydroxyethylamine compounds of formula (I): (I) having Asp2 (-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated-amyloid levels or-amyloid deposits, particularly Alzheimer's disease.
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Page 76

(2010/02/07)

TRICYCLIC INDOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER’S DISEASE
The present invention relates to novel hydroxyethylamine compounds having Asp2 (β-secretase, BACE1 or Memapsin) inhibitory activity, processes for their preparation, to compositions containing them and to their use in the treatment of diseases characterised by elevated β- amyloid levels or β-amyloid deposits, particularly Alzheimer's disease.
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Page 28

(2010/02/09)

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Chemical Properties

Boiling Point: 196.8±35.0 °C(Predicted)
Density: 1.149±0.06 g/cm3(Predicted)
PKA: 9.04±0.10(Predicted)
PSA: 26.02000
LogP: 3.59950

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