153576-31-9Relevant articles and documents
Acid Catalyzed α-Alkylation of β-Aminothiophenes with Aldehydes. Synthesis of 2-Alkyl 3-thiophenamines, Bis(3-amino-2-thienyl)-methane Derivatives and Dithieno[3,2-b:2′,3′-e]pyridines
Berkaoui, M'hamed,Outurquin, Francis,Paulmier, Claude
, p. 9 - 14 (2007/10/03)
The acid catalyzed reaction of 3-thiophenamines with aldehydes in the presence of selenophenol as the reducing agent, gives 2-alkyl-3-thiophenamines. Without reduction, bis(3-amino-2-thienyl)methane derivatives have been obtained and transformed into dith
Acid Catalyzed α-Alkylation of β-Aminothiophenes Using Aldehydes and Selenophenol. Synthesis of Bis(3-amino-2-thienyl)methane Derivatives
Outurquin, Francis,Paulmier, Claude
, p. 5715 - 5718 (2007/10/02)
The acid-catalyzed reaction between β-aminothiophenes and aldehydes, in the presence of selenophenol, leads to α-alkyl β-aminothiophenes.The reduction step is not observed with thiophenol.Without selenol, a second alkylation reaction occurs and bis(3-amin