153797-65-0 Usage
Uses
Used in Organic Synthesis:
Formamide, N-(3-fluoro-2-methylphenyl)(9CI) is used as a reagent in organic synthesis for the preparation of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis of pharmaceuticals and other organic compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, Formamide, N-(3-fluoro-2-methylphenyl)(9CI) is used as a building block for the development of new drugs. Its fluorinated and methylated phenyl ring can impart specific biological activities to the resulting drug molecules, potentially leading to the discovery of novel therapeutic agents.
Used in Agrochemical Development:
Formamide, N-(3-fluoro-2-methylphenyl)(9CI) may also have potential applications in the development of new agrochemicals. Its unique chemical properties can be harnessed to create effective pesticides or herbicides, contributing to advancements in agricultural chemistry.
However, due to its potential toxicity and environmental impact, proper handling and disposal procedures should be followed when working with Formamide, N-(3-fluoro-2-methylphenyl)(9CI). This ensures the safety of researchers and minimizes any negative effects on the environment.
Check Digit Verification of cas no
The CAS Registry Mumber 153797-65-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,3,7,9 and 7 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 153797-65:
(8*1)+(7*5)+(6*3)+(5*7)+(4*9)+(3*7)+(2*6)+(1*5)=170
170 % 10 = 0
So 153797-65-0 is a valid CAS Registry Number.
153797-65-0Relevant articles and documents
Copper-(II) Catalyzed N-Formylation and N-Acylation of Aromatic, Aliphatic, and Heterocyclic Amines and a Preventive Study in the C-N Cross Coupling of Amines with Aryl Halides
Sonawane, Rahul B.,Rasal, Nishant K.,Bhange, Dattatraya S.,Jagtap, Sangeeta V.
, p. 3907 - 3913 (2018/09/12)
A Cu-(II) catalyzed N-formylation and N-acylation of amines with moderate to excellent yields, using N, N-dimethyl formamide (DMF) and N, N-dimethyl acetamide (DMA) as a formyl and acylating sources in the presence of 1,2,4-triazole is reported. This novel, highly efficient and simple protocol shows broad substrate scope for aliphatic, aromatic, and heterocyclic amines. In addition, the conditions to prevent N-formylation and N-acylation impurities in the C?N cross coupling of amines and aryl halides are described typically when DMF and DMA are used as solvents, with various catalysts, ligands, and bases.
Nickel-(II)-Catalyzed N-Formylation and N-Acylation of Amines
Sonawane, Rahul B.,Rasal, Nishant K.,Jagtap, Sangeeta V.
supporting information, p. 2078 - 2081 (2017/04/28)
A highly efficient protocol of Ni(II) metal complex, [Ni(quin)2], catalyzing N-formylation and N-acylation of amines with moderate to excellent yields, using N,N-dimethylformamide and N,N-dimethylacetamide in the presence of imidazole, is described here. The protocol shows broad substrate scope for aliphatic, aromatic, and heterocyclic amines.
