Monoaromatic miazine HIV-1 reverse transcriptase inhibitor containing triazole rings and preparation method and application thereof
The invention relates to a monoaromatic miazine HIV-1 reverse transcriptase inhibitor containing triazole rings and a preparation method and application thereof. The compound has the structure shown as the formula I or II. The invention further relates to
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Paragraph 0050-0052
(2019/08/26)
Pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and preparation method and application thereof
The invention provides pyrimidine heterocyclic compounds, pyrimidine heterocyclic compound salts, and a preparation method and application thereof. According to the pyrimidine heterocyclic compounds provided by the invention, specific Rq is selected, so that the obtained compounds have favorable drug resistance and long half life when being used as the medicine for treating or preventing HIV. The compounds have the advantages of high activity, low toxicity and high stability.
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Paragraph 0137; 0142; 0143; 0144
(2017/07/26)
PROCESS FOR RILPIVIRINE USING NOVEL INTERMEDIATE
The present invention provides a commercially viable process for preparing rilpivirine and its pharmaceutically acceptable acid addition salts thereof in high yields using novel intermediate.
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Page/Page column 8
(2014/02/15)
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