154365-44-3

Basic information

• Product Name: 3,4-Dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid
• Synonyms: 3,4-Dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid;2-Methyl-6-nitro-3-oxo-3,4-dihydro-2H-benzo[1,4]oxazine-2-carboxylic acid
• CAS NO: 154365-44-3
• Molecular Formula: C₁₀H₈N₂O₆
• Molecular Weight: 252.18032
• Mol File: 154365-44-3.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,4-Dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-Dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid(154365-44-3)
• EPA Substance Registry System: 3,4-Dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid(154365-44-3)

Safety Data

• Hazardous Substances Data: 154365-44-3(Hazardous Substances Data)

Upstream product

• 154365-37-4 3,4-dihydro-2-methyl-6-nitro-3-oxo-2H-1,4-benzoxazine-2-carboxylic acid ethyl ester 
• 99-57-0 2-hydroxy-5-nitroaniline 

Downstream Products

• 727994-02-7 benzyl (2S)-1-{[(2R)-2-methyl-6-nitro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]carbonyl}-2-pyrrolidinecarboxylate 
• 727994-00-5 benzyl (2S)-1-{[(2S)-2-methyl-6-nitro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]carbonyl}-2-pyrrolidinecarboxylate 
• 727994-20-9 ethyl (2S)-1-{[(2R)-6-({4-[amino(imino)methyl]benzoyl}amino)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]carbonyl}-2-pyrrolidinecarboxylate 
• 727994-17-4 ethyl (2S)-1-{[(2S)-6-({4-[amino(imino)methyl]benzoyl}amino)-2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]carbonyl}-2-pyrrolidinecarboxylate 

Relevant articles and documents

Conformationally tailored N-[(2-methyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)carbonyl]proline templates as molecular tools for the design of peptidomimetics. Design and synthesis of fibrinogen receptor antagonists.

The proline peptide bond was shown by 2D proton NMR studies to exist exclusively in the trans conformation in benzyl (2S)-1-[[(2S)-2-methyl-6-nitro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl]carbonyl]-2-pyrrolidinecarboxylate [(S,S)-11], benzyl (2S)-1-[[(2S