154366-45-7Relevant articles and documents
Acyl Migrations on 3(5)-Amino-pyrazole
Graubaum, Heinz
, p. 585 - 588 (1993)
3(5)-Amino-pyrazole 1 form 3 isomeric monoacylation products, 4-diacylation products and 3-triacylation products by reaction with electrophiles like cyanates, isocyanates or carboxylic and chlorides, respectively.Acyl migrations are observed depending on the reaction temperature and the structure of the acyl residue.The structures of the acyl derivatives of 3(5)-amino-pyrazole were characterized by nmr-spectroscopy.
PYRAZOLO (1,5A) 1,3,5-TRIAZINES
-
, (2014/02/13)
Pyrazolo[1,5a]1,3,5-triazines are disclosed which are useful as inhibitors of phosphodiesterase enzymes or intermediate in the production process. Such triazines are of general structure: wherein R1, R2 and R3 are as defined hereinafter, or heterocyclic derivatives thereof. Also disclosed are substituted pyrazole derivatives which are used to prepare the pyrazolo[1,5a]1,3,5-triazines of this invention