Cytochrome P450-mediated metabolism of haloperidol and reduced haloperidol to pyridinium metabolites
Haloperidol (HP) has been reported to undergo cytochrome P450 (P450)-mediated metabolism to potentially neurotoxic pyridinium metabolites; however, the chemical pathways and specific enzymes involved in these reactions remain to be identified. The aims of
Avent, Kathryn M.,DeVoss,Gillam, Elizabeth M. J.
p. 914 - 920
(2008/01/27)
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