- Tuning the Reactivity of Peroxo Anhydrides for Aromatic C-H Bond Oxidation
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Phenol moieties are key structural motifs in many areas of chemical research from polymers to pharmaceuticals. Herein, we report on the design and use of a structurally demanding cyclic peroxide (spiro[bicyclo[2.2.1]heptane-2,4′-[1,2]dioxolane]-3′,5′-dione, P4) for the direct hydroxylation of aromatic substrates. The new peroxide benefits from high thermal stability and can be synthesized from readily available starting materials. The aromatic C-H oxidation using P4 exhibits generally good yields (up to 96%) and appreciable regioselectivities.
- Pilevar, Afsaneh,Hosseini, Abolfazl,?ekutor, Marina,Hausmann, Heike,Becker, Jonathan,Turke, Kevin,Schreiner, Peter R.
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p. 10070 - 10079
(2018/09/06)
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- NOVEL DIVINYL-ETHER COMPOUND AND MANUFACTURING METHOD THEREFOR
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A novel divinyl ether compound having the formula (I): wherein A indicates a single bond or a double bond which is low in odor, low in volatility, and low in skin irritability, which have low toxicities, which are useful as a starting material for a polymer composition having excellent curability, adhesiveness and transmission in the ultraviolet light region, and further, having a special reactivity alone or with other compounds, and a process for producing the same.
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Paragraph 0032
(2013/07/19)
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- Hydroxyl-containing monomer, polymer, resist composition, and patterning process
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A hydroxyl-containing monomer of formula (1) is provided wherein R1 is H, F, methyl or trifluoromethyl, R2 and R3 are monovalent C1-C15 hydrocarbon groups, or R2 and R3 may form an aliphatic ring. The monomers are useful for the synthesis of polymers which have high transparency to radiation of up to 500 nm and the effect of controlling acid diffusion so that the polymers may be used as a base resin to formulate radiation-sensitive resist compositions having a high resolution.
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Page/Page column 40-41
(2009/10/01)
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- DERMATOLOGICAL COMPOSITIONS AND METHODS
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Disclosed are methods and compositions for regulating the melanin content of mammalian melanocytes; regulating pigmentation in mammalian skin, hair, wool or fur; treating or preventing various skin and proliferative disorders; by administration of various compounds, including alcohols, diols and/or triols and their analogues.
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- Treatment of neurodegenerative diseases
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Disclosed are methods for increasing the differentiation of mammalian neuronal cells for purposes of treating neurodegenerative diseases or nerve damage by administration of various compounds including alcohols, diols and/or triols and their analogues.
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- Treatment of diseases mediated by the nitric oxide/cGMP/protein kinase G pathway
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Disclosed are methods and compositions for stimulating cellular nitric oxide (NO) synthesis, cyclic guanosine monophosphate levels (cGMP), and protein kinase G (PKG) activity for purposes of treating diseases mediated by deficiencies in the NO/cGMP/PKG signal transduction pathway, by administration of various compounds including alcohols, diols and/or triols and their analogues.
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- 2,4-Dioxa-7,10-methano-spiro [5,5] undecanes and their use in perfumery compositions
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2,4-dioxa-7,10-methano-spiro [5,5] undecanes having the formula STR1 wherein R is a member selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms, vinyl and propenyl and their isomeric mixtures; its synthesis, its use as a perfumery agent and as an olefactant component in perfumery compositions and as an odorant for technical products.
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