154590-34-8

Basic information

• Product Name: tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate
• Synonyms: 4-(2-Fluoro-4-nitrophenyl)piperazine, N1-BOC protected;tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate;1-Boc-4-(2-Fluoro-4-nitrophenyl)piperazine, 97%;3-Fluoro-4-[4-(tert-butoxycarbonyl)piperazin-1-yl]nitrobenzene
• CAS NO: 154590-34-8
• Molecular Formula: C₁₅H₂₀FN₃O₄
• Molecular Weight: 325.3354032
• Mol File: 154590-34-8.mol

Chemical Properties

• Melting Point: 153-155 °C(Solv: ethyl ether (60-29-7))
• Boiling Point: 453.5±45.0 °C(Predicted)
• Appearance: /Solid
• Density: 1.270±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.11±0.10(Predicted)
• CAS DataBase Reference: tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate(154590-34-8)
• EPA Substance Registry System: tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate(154590-34-8)

Safety Data

• Hazardous Substances Data: 154590-34-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Drug Development:
Tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate is used as a research compound for investigating the biological activities and pharmacological properties of piperazine-based molecules. Its unique structure and functional groups allow researchers to explore its potential applications in various therapeutic areas.
Used in Medicinal Formulations:
tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate's tert-butyl ester group contributes to its stability and bioavailability in medicinal formulations. This makes it a valuable component in the development of new drugs and pharmaceutical products, enhancing their efficacy and safety.
Used in Chemical Synthesis:
Tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate can be used as a starting material or intermediate in the synthesis of other piperazine-based compounds with potential pharmaceutical applications. Its versatile structure allows for further functionalization and modification to create new molecules with desired properties.
Used in Drug Design and Optimization:
tert-Butyl 4-(2-fluoro-4-nitrophenyl)piperazine-1-carboxylate's structure and functional groups provide a foundation for drug design and optimization efforts. Researchers can use it as a template to develop new piperazine-based drugs with improved pharmacokinetic and pharmacodynamic profiles, targeting specific diseases and conditions.

Upstream product

• 24424-99-5 di-tert-butyl dicarbonate 
• 154590-33-7 1-(2-fluoro-4-nitrophenyl)piperazine 
• 369-34-6 3,4-difluoronitrobenzene 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 154590-40-6 3-[3-Fluoro-4-(4-tert-butoxycarbonylpiperazin-1-yl)phenyl]-5-methanesulfonyloxymethyl-2-oxazolidinone 

Downstream Products

• 154590-35-9 tert-butyl 4-(4-amino-2-fluorophenyl)piperazine-1-carboxylate 
• 154590-62-2 (R)-tert-butyl-4-(2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenyl)piperazine-1-carboxylate 
• 154590-64-4 (S)-N-[3-[3-fluoro-4-[N-t-butoxycarbonylpiperazin-1-yl]phenyl]-2-oxooxazolidin-5-ylmethyl]azide 
• 268209-15-0 tert-butyl 4-(4-((S)-5-(aminomethyl)-2-oxooxazolidin-3-yl)-2-fluorophenyl)piperazine-1-carboxylate 
• 154590-36-0 tert-butyl 4-(4-(benzyloxycarbonyl)-2-fluorophenyl)piperazine-1-carboxylate 
• 154590-65-5 (S)-N-{[3-[3-fluoro-4-(N-4-tert-butoxycarbonylpiperazin-1-yl)phenyl]-2-oxo-5-oxazolidinyl]methyl}acetamide 
• 154590-63-3 [N-3-(1-tert-butoxycarbonyl)-4-(2-fluoro-4-piperazinyl)-2-oxo-5-oxazolidinyl]methyl methanesulfonate 
• 392659-24-4 N-(3-{3-fluoro-4-[4-(5-formyl-furan-2-ylmethyl)-piperazin-1-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl)-acetamide 
• 548762-76-1 N-(3-{3-fluoro-4-[4-(5-hydroxymethyl-furan-2-ylmethyl)-piperazin-1-yl]-phenyl}-2-oxo-oxazolidin-5-ylmethyl)-acetamide 
• 548762-73-8 N-[3-(3-fluoro-4-{4-[5-(hydroxyimino-methyl)-furan-2-ylmethyl]-piperazin-1-yl}-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide 

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