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2-(1H-indol-3-yl)-2-methylpropan-1-amine, commonly known as Alpha-methyltryptamine (AMT), is a psychoactive drug derived from the amino acid tryptophan. It exhibits stimulant and hallucinogenic properties, producing effects akin to amphetamine and LSD. Despite its recreational use for euphoric and psychedelic experiences, AMT is associated with harmful side effects, including increased heart rate, agitation, and the risk of overdose. Due to its potential for abuse and addiction, it is classified as a controlled substance in many countries, with its use being illegal in numerous jurisdictions.

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  • 15467-31-9 Structure
  • Basic information

    1. Product Name: 2-(1H-indol-3-yl)-2-methylpropan-1-amine
    2. Synonyms: 2-(1H-indol-3-yl)-2-methylpropan-1-amine;1H-Indole-3-ethanaMine, b,b-diMethyl-;3-(2-Amino-tert-butyl)indole;beta,beta-Dimethyltryptamine
    3. CAS NO:15467-31-9
    4. Molecular Formula: C12H16N2
    5. Molecular Weight: 188.272
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 15467-31-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 347.3°Cat760mmHg
    3. Flash Point: 190.7°C
    4. Appearance: /
    5. Density: 1.093
    6. Vapor Pressure: 5.45E-05mmHg at 25°C
    7. Refractive Index: 1.619
    8. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-(1H-indol-3-yl)-2-methylpropan-1-amine(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-(1H-indol-3-yl)-2-methylpropan-1-amine(15467-31-9)
    12. EPA Substance Registry System: 2-(1H-indol-3-yl)-2-methylpropan-1-amine(15467-31-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15467-31-9(Hazardous Substances Data)

15467-31-9 Usage

Uses

Used in Recreational Drug Use:
2-(1H-indol-3-yl)-2-methylpropan-1-amine is used as a psychoactive substance for its euphoric and hallucinogenic effects, providing users with experiences similar to those induced by amphetamine and LSD.
Used in Research and Development:
Although not explicitly mentioned in the provided materials, 2-(1H-indol-3-yl)-2-methylpropan-1-amine may be utilized in scientific research for understanding the mechanisms of action of psychoactive substances and developing potential therapeutic agents. However, this application is subject to strict regulations and ethical considerations due to the drug's controlled status and potential for abuse.

Check Digit Verification of cas no

The CAS Registry Mumber 15467-31-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,4,6 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 15467-31:
(7*1)+(6*5)+(5*4)+(4*6)+(3*7)+(2*3)+(1*1)=109
109 % 10 = 9
So 15467-31-9 is a valid CAS Registry Number.
InChI:InChI=1/C12H16N2/c1-12(2,8-13)10-7-14-11-6-4-3-5-9(10)11/h3-7,14H,8,13H2,1-2H3

15467-31-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(1H-indol-3-yl)-2-methylpropan-1-amine

1.2 Other means of identification

Product number -
Other names 2-indol-3-yl-2-methyl-propylamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15467-31-9 SDS

15467-31-9Relevant articles and documents

Benzylamine derivatives and its application on the medicament

-

, (2017/08/25)

The invention provides novel benzylamine derivatives or stereoisomers, geometric isomers, tautomers, nitrogen oxides, hydrates, solvates, metabolites and pharmaceutically acceptable salts or pro-drugs thereof for treating Alzheimer diseases. The invention also provides a medicine composition containing a compound provided by the invention and a method for treating the Alzheimer diseases by using the compound or the medicine composition of the compound provided by the invention.

Substituted heterocyclic compound and its application on the medicament

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, (2016/10/09)

The invention provides a novel substituted heterocyclic compound or stereisomers, stereomers, tautomers, oxynitrides, hydrates, solvates, metabolites, and pharmaceutically acceptable salts or prodrugs thereof. The novel substituted heterocyclic compound i

Discovery of XL335 (WAY-362450), a highly potent, selective, and orally active agonist of the farnesoid X receptor (FXR)

Flatt, Brenton,Martin, Richard,Wang, Tie-Lin,Mahaney, Paige,Murphy, Brett,Gu, Xiao-Hui,Foster, Paul,Li, Jiali,Pircher, Parinaz,Petrowski, Mary,Schulman, Ira,Westin, Stefan,Wrobel, Jay,Yan, Grace,Bischoff, Eric,Daige, Chris,Mohan, Raju

supporting information; experimental part, p. 904 - 907 (2009/12/24)

Azepino[4,5-b]indoles have been identified as potent agonists of the farnesoid X receptor (FXR). In vitro and in vivo optimization has led to the discovery of 6m (XL335, WAY-362450) as a potent, selective, and orally bioavailable FXR agonist (EC50 = 4 nM, Eff = 149%). Oral administration of 6m to LDLR-/- mice results in lowering of cholesterol and triglycerides. Chronic administration in an atherosclerosis model results in significant reduction in aortic arch lesions.

NOVEL TRICYCLIC HETEROCYCLE COMPOUND

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Page/Page column 59, (2008/06/13)

―The present invention relates to the compound represented by formula (I) ????????A―X―Y―Z―B?????(I) (wherein A is a cyclic group which may have a substituent(s); X is a single bond or a spacer; Y is a single bond or a spacer; Z is a single bond or a spacer; B is a hydrocarbon group which may have a substituent(s) or a cyclic group which may have a substituent(s)), a salt thereof, a solvate thereof or a prodrug thereof. The compound represented by formula (I), a salt thereof, a solvate thereof or a prodrug thereof is useful for preventive and/or therapeutic agent for a disease caused by stress.

-3 (SULFONAMIDOETHYL) -INDOLE DERIVATIES FOR USE AS GLUCOCORTICOID MIMETICS IN THE TREATMENT OF INFLAMMATORY, ALLERGIC AND PROLIFERATIVE DISEASES

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Page/Page column 67, (2010/02/06)

Compounds of Formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, and Y are as defined herein, or a tautomer, prodrug, solvate, or sal

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