Fungicidal and genotoxic activity of new substituted pyridazinones
Some 2-sulfonyl- and 2-acylderivatives of the 4,5-dichloro-3 (2H)- pyridazinone were prepared in order to test their fungicidal activity. Interesting results, both in vitro and in vivo, were obtained in particular from the alkylsulfonyl-derivatives. Genotoxic activity of 3(2H)-pyridazinones was evaluated in vitro by the Bacillus subtilis rec-assay and the Salmonella- microsome reversion assay.
Carmellino,Massolini,Pagani,Zani,Leri
p. 1427 - 1438
(2007/10/02)
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