A new synthetic route to macrocycles: Synthesis of large ring enaminolactones
Macrocyclic enaminolactones 5 are prepared in three steps from commercially available chloroalcohols 1. The cyclization step is performed by intramolecular nucleophilic addition of the hydroxy group to an aminomethyleneketene generated by thermolysis.
Jourdain,Pommelet
p. 1545 - 1548
(2007/10/02)
More Articles about upstream products of 155373-45-8