155403-06-8

Basic information

• Product Name: 5-AMINO-2-IODOBENZOTRIFLUORIDE
• Synonyms: 5-AMINO-2-IODOBENZOTRIFLUORIDE;4-Iodo-3-(trifluoromethyl)aniline;5-Amino-2-iodobenzotrifluoride 98%;5-Amino-2-iodobenzotrifluoride98%;4-Iodo-3-(trifluoromethyl)aniline, 4-Iodo-alpha,alpha,alpha-trifluoro-m-toluidine;4-Iodo-3-trifluoromethyl-phenylamine;4-iodo-3-(trifluoromethyl)Benzenamine
• CAS NO: 155403-06-8
• Molecular Formula: C7H5F3IN
• Molecular Weight: 287.02
• Mol File: 155403-06-8.mol

Chemical Properties

• Boiling Point: 268.2°Cat760mmHg
• Flash Point: 116°C
• Appearance: Off-white/Solid
• Density: 1.948g/cm³
• Water Solubility: Slightly soluble in water.
• Sensitive: Light Sensitive
• CAS DataBase Reference: 5-AMINO-2-IODOBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-AMINO-2-IODOBENZOTRIFLUORIDE(155403-06-8)
• EPA Substance Registry System: 5-AMINO-2-IODOBENZOTRIFLUORIDE(155403-06-8)

Safety Data

• Hazard Codes: Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 26-36/37/39
• HazardClass: 6.1
• Hazardous Substances Data: 155403-06-8(Hazardous Substances Data)

Usage

Uses

Used in Agrochemicals:
5-AMINO-2-IODOBENZOTRIFLUORIDE is used as a key intermediate in the development of agrochemicals for [application reason]. Its unique chemical properties allow for the creation of novel compounds with enhanced pesticidal, herbicidal, or fungicidal activities, contributing to improved crop protection and yield.
Used in Pharmaceuticals:
In the pharmaceutical industry, 5-AMINO-2-IODOBENZOTRIFLUORIDE is utilized as an essential building block for the synthesis of various drug molecules. Its incorporation into drug candidates can lead to the development of new therapeutic agents with improved pharmacological properties, such as increased potency, selectivity, or bioavailability.
Used in Dyestuff:
5-AMINO-2-IODOBENZOTRIFLUORIDE is also employed as an intermediate in the production of dyestuffs. Its distinctive molecular structure enables the creation of novel dyes with unique color properties, which can be applied in various industries, such as textiles, plastics, and printing inks, to achieve vibrant and long-lasting colorations.
Used in Organic Syntheses:
As an important organic intermediate, 5-AMINO-2-IODOBENZOTRIFLUORIDE is widely used in organic synthesis for the preparation of a diverse range of chemical compounds. Its reactivity and functional group compatibility make it a valuable component in the synthesis of complex organic molecules, including those with potential applications in materials science, chemical research, and specialty chemicals.

Upstream product

• 400-75-9 1-iodo-4-nitro-2-(trifluoromethyl)benzene 

Downstream Products

• 654-70-6 4-amino-2-trifluoromethylbenzonitrile 

Relevant articles and documents

PHENYLACETAMIDES SUITABLE AS PROTEIN KINASE INHIBITORS

The invention relates to compounds of the formula (I) wherein the moieties R1 , R2, R3, R9, R10 and Q and X, Y and Z are as defined in the specification, and salts thereof; as well as their use, methods of use for them and method of their synthesis, and the like. The compounds are protein kinase inhibitors and can, inter alia, be used in the treatment of various proliferative diseases.

Isoquinoline derivatives with angiogenesis inhibiting activity

The invention relates to compounds of formula I wherein r is from 0 to 2; n is from 0 to 2; m is from 0 to 4; A, B, D and E are each independently of the others N or CH, with the proviso that not more than two of those radicals are N; G is lower alkylene, —CH2—O—, —CH2—S—, —CH2—NH—, oxa (—O—), thia (—S—) or imino (—NH—), or is lower alkylene substituted by acyloxy or by hydroxy; Q is lower alkyl, especially methyl; R is H or lower alkyl; X is imino, oxa or thia; Y is lower alkyl or, especially, aryl, heteroaryl or unsubstituted or substituted cycloalkyl; and Z is amino, mono- or di-substituted amino, halogen, alkyl, substituted alkyl, hydroxy, etherified or esterified hydroxy, nitro, cyano, carboxy, esterified carboxy, alkanoyl, carbamoyl, N-mono- or N,N-di-substituted carbamoyl, amidino, guanidino, mercapto, sulfo, phenylthio, phenyl-lower alkylthio, alkylphenylthio, phenylsulfinyl, phenyl-lower alkylsulfinyl, alkylphenyl-sulfinyl, phenylsulfonyl, phenyl-lower alkanesulfonyl or alkylphenylsulfonyl, and where, if more than one radical Z is present (m≧4), the substituents Z are identical or different; and wherein the bonds indicated by a wavy line are either single bonds or double bonds; or an N-oxide of the mentioned compound, wherein one or more N atoms carry an oxygen atom; or a salt thereof. The compounds inhibit especially angiogenesis.