METHODS OF TREATING COGNITIVE IMPAIRMENT AND DEMENTIA
This invention relates to methods for treating, managing and preventing cognitive impairment associated with various diseases and disorders, age-associated memory impairment, and dementia.
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Page/Page column 76
(2008/12/06)
Synthesis of some piperazinylpyrazolo[3,4-b]pyridines as selective serotonin re-uptake inhibitors
A number of 3-substituted 6-piperazinylpyrazolo[3,4-b]pyridines were synthesized from 2,6-difluoropyridine by directed ortho metallation and sequential intra- and intermolecular displacement of fluorine. Three derivatives with a cyano group in the 3-position showed activity as selective serotonin re-uptake inhibitors.
Shutske, Gregory M.,Roehr, Joachim E.
p. 789 - 795
(2007/10/03)
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