155826-26-9

Basic information

• Product Name: 4-Piperidinecarboxaldehyde, 1-acetyl- (9CI)
• Synonyms: 4-Piperidinecarboxaldehyde, 1-acetyl- (9CI);1-acetyl-4-Piperidinecarboxaldehyde;4-Piperidinecarboxal
• CAS NO: 155826-26-9
• Molecular Formula: C₈H₁₃NO₂
• Molecular Weight: 155.19432
• Product Categories: ALDEHYDE;ACETYLGROUP
• Mol File: 155826-26-9.mol

Chemical Properties

• Appearance: /
• Storage Temp.: Inert atmosphere,Store in freezer, under -20°C
• CAS DataBase Reference: 4-Piperidinecarboxaldehyde, 1-acetyl- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Piperidinecarboxaldehyde, 1-acetyl- (9CI)(155826-26-9)
• EPA Substance Registry System: 4-Piperidinecarboxaldehyde, 1-acetyl- (9CI)(155826-26-9)

Safety Data

• Hazardous Substances Data: 155826-26-9(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-Piperidinecarboxaldehyde, 1-acetyl(9CI) is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure allows for the development of new drugs with potential applications in the treatment of neurological and psychiatric disorders, as well as anti-cancer properties.
Used in Agrochemical Industry:
In the agrochemical industry, 4-Piperidinecarboxaldehyde, 1-acetyl(9CI) serves as a building block for the preparation of agrochemicals. Its incorporation into these compounds can lead to the development of new pesticides or herbicides with improved efficacy and selectivity.
Used in Organic Synthesis:
4-Piperidinecarboxaldehyde, 1-acetyl(9CI) is used as a versatile reagent in organic synthesis. Its acetyl and carboxaldehyde functional groups enable a wide range of chemical reactions, making it a valuable component in the synthesis of fine chemicals and natural products.
Used in Research and Development:
4-Piperidinecarboxaldehyde, 1-acetyl(9CI) is utilized in research and development for its potential applications in various fields. Its unique structure and reactivity make it an interesting candidate for the development of new compounds with novel properties and therapeutic potential.

Upstream product

• 7755-92-2 piperazine-1-carbaldehyde 
• 830-03-5 4-nitrophenol acetate 
• 846057-27-0 1-[4-(hydroxymethyl)piperidin-1-yl]ethan-1-one 
• 6457-49-4 4-piperidinemethanol 
• 69001-10-1 1-acetyl-piperidine-4-carboxylic acid ethyl ester 

Downstream Products

• 1272656-31-1 methyl [(1S)-1-({(2S)-2-[4-(4′-{2-[8-acetyl-2-((2S)-3-methyl-2-{[(methyloxy)carbonyl]amino}butanoyl)-2,8-diazaspiro[4.5]-dec-3-yl]-1H-imidazol-4-yl}-4-biphenylyl)-1H-imidazol-2-yl]-1-pyrrolidinyl}carbonyl)-2-methylpropyl]carbamate 
• 1360889-99-1 C₂₇H₂₉N₅O 

Relevant articles and documents

PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES HAVING MULTIMODAL ACTIVITY AGAINST PAIN

The present invention relates to pyrazolopyrimidine derivatives having dual pharmacological activity towards both the α2δ subunit of the voltage-gated calcium channel and the sigma-1 (σ1) receptor, to processes of preparation of such compounds,

HETEROCYCLIC COMPOUND INTERMEDIATE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

Disclosed by the invention is a heterocyclic compound, an intermediate, and a preparation method therefor and an application thereof. Provided by the invention are a heterocyclic compound as shown in formula I, and a stereoisomer, a geometric isomer, a tautomer, a nitrogen oxide, a hydrate, a solvate, a metabolite, an ester, a pharmaceutically acceptable salt or a prodrug thereof. The heterocyclic compound hasa high P2X3 antagonistic activity, and has good selectivity, low toxicity, good metabolic stability and little taste influence.

Reaction Mechanism in Ionic Liquids: Kinetics and Mechanism of the Aminolysis of 4-Nitrophenyl Acetate

In this work, we report a kinetic study of the reactions of the title compound with secondary alicyclic amines at different temperatures in acetonitrile and several ionic liquids (ILs). From this study, we have described that the reactions in MeCN and in

Novel spiroketal pyrrolidine GSK2336805 potently inhibits key hepatitis C virus genotype 1b mutants: From lead to clinical compound

Rapid clinical progress of hepatitis C virus (HCV) replication inhibitors, including these selecting for resistance in the NS5A region (NS5A inhibitors), promises to revolutionize HCV treatment. Herein, we describe our explorations of diverse spiropyrrolidine motifs in novel NS5A inhibitors and a proposed interaction model. We discovered that the 1,4-dioxa-7-azaspiro[4.4]nonane motif in inhibitor 41H (GSK2236805) supported high potency against genotypes 1a and 1b as well as in genotype 1b L31V and Y93H mutants. Consistent with this, 41H potently suppressed HCV RNA in the 20-day RNA reduction assay. Pharmacokinetic and safety data supported further progression of 41H to the clinic.