155880-00-5Relevant articles and documents
The Desferrithiocin Pharmacophore
Bergeron, Raymond J.,Liu, Charles Z.,McManis, James S.,Xia, Michael X. B.,Algee, Samuel E.,Wiegand, Jan
, p. 1411 - 1417 (1994)
The (S)-desferrithiocin (DFT) skeleton is shown to be a useful pharmacophore on which to design orally effective iron chelators.While the study clearly indicates that formal reduction of the desazadesmethyldesferrithiocin thiazoline to a thiazolidine (6),