Structure-Activity Relationship Studies of Central Nervous System Agents. 13. 4--1-(2-methoyphenyl)piperazine, a new Putative 5HT1A Receptor Antagonist, and Its Analogs
A new set of 4-alkyl-1-(o-methoxyphenyl)piperazines containing a terminal benzotriazole fragment were synthesized, and their 5-HT1A and 5-HT2 affinity was determined.It was shown that the benzotriazole moiety contributes to both the
Mokrosz, Jerzy L.,Paluchowska, Maria H.,Chojnacka-Wojcik, Ewa,Filip, Malgorzata,Charakchieva-Minol, Sijka,et al.