156576-12-4 Usage
Explanation
Represents the chemical composition of the compound, consisting of 11 carbon atoms, 10 hydrogen atoms, 2 nitrogen atoms, and 1 oxygen atom.
Explanation
The compound contains a ring structure with atoms of different elements, specifically carbon, nitrogen, and oxygen.
Explanation
The compound features a benzimidazole ring, which is a fused ring system consisting of a benzene ring and an imidazole ring.
Explanation
A methyl group (CH3) is attached to the third carbon of the ring, which can influence the compound's properties and potential applications.
Explanation
The compound may exhibit biological activities, making it a candidate for further research in the development of new drugs.
Explanation
Due to its potential biological activities, the compound can be of interest in pharmaceutical research for the development of new drugs.
Explanation
The "9CI" designation indicates that this is the name according to the CAS conversion of the systematic name, which is a standardized way of naming chemical compounds.
Explanation
The compound may have potential pharmacological properties, making it of interest in the field of medicinal chemistry for further exploration and development.
Heterocyclic Compound
Yes
Benzimidazole Ring
Present
3-Methyl Substitution
Yes
Potential Biological Activities
Possible
Pharmaceutical Research
Relevance
Medicinal Chemistry
Interest
Check Digit Verification of cas no
The CAS Registry Mumber 156576-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,5,7 and 6 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 156576-12:
(8*1)+(7*5)+(6*6)+(5*5)+(4*7)+(3*6)+(2*1)+(1*2)=154
154 % 10 = 4
So 156576-12-4 is a valid CAS Registry Number.
156576-12-4Relevant articles and documents
Sustainable Synthesis of 2-Hydroxymethylbenzimidazoles using D-Fructose as a C2 Synthon
Raja, Dineshkumar,Philips, Abigail,Sundaramurthy, Devikala,Chandru Senadi, Gopal
supporting information, p. 3754 - 3759 (2021/10/14)
D-fructose, a biomass-derived carbohydrate has been identified as an environmentally benign C2 synthon in the preparation of synthetically useful 2-hydroxymethylbenzimidazole derivatives by coupling with 1,2-phenylenediamines. Proof of concept was established by synthesizing 23 examples using BF3.OEt2 (20 mol%), TBHP (5.5 M, decane) (1.0 equiv.) in CH3CN at 90 °C for 1 h. The pivotal features of this method include metal-free conditions, short time, good functional group tolerance, gram scale feasibility and the synthesis of benzimidazole fused 1,4-oxazine. Control studies with conventional C2 synthons did not produce the desired product, thus suggesting a new reaction pathway from D-fructose.
LE 2-HYDROXYMETHYLBENZIMIDAZOLE PRECURSEUR DE SYNTHESE DE NOUVEAUX SYSTEMES HETEROCYCLIQUES
Essassi, E. M.,Fifani, J.,Hamamsi, I.
, p. 83 - 84 (2007/10/02)
The easy synthesis of 2-hydroxymethylbenzimidazole, leads us to use this compound in the preparation of new heterocyclic systems.
