156601-79-5 Usage
Uses
Used in Pharmaceutical Industry:
Nepaprazole is used as a proton pump inhibitor for its potent ability to inhibit gastric acid secretion. This makes it a valuable treatment option for conditions such as gastroesophageal reflux disease (GERD), peptic ulcers, and other acid-related disorders. Its enhanced potency compared to Omeprazole suggests that it may offer improved efficacy and faster relief for patients suffering from these conditions.
Additionally, Nepaprazole's antisecretory activity indicates its potential use in reducing the secretion of various substances in the body, which could have further applications in treating a range of medical conditions beyond gastrointestinal disorders. However, more research would be needed to explore these potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 156601-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,6,6,0 and 1 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 156601-79:
(8*1)+(7*5)+(6*6)+(5*6)+(4*0)+(3*1)+(2*7)+(1*9)=135
135 % 10 = 5
So 156601-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C18H19N3O2S/c1-23-15-10-11-19-17-12(15)6-2-5-9-16(17)24(22)18-20-13-7-3-4-8-14(13)21-18/h3-4,7-8,10-11,16H,2,5-6,9H2,1H3,(H,20,21)/t16-,24+/m1/s1
156601-79-5Relevant articles and documents
Syntheses and antiulcer activities of novel 2-[(6,7,8,9-tetrahydro-5H- cyclohepta[b]pyridin-9-yl)sulfinyl]-1H-benzimidazole analogues
Yamada,Goto,Shimanuki,Narita
, p. 718 - 720 (1994)
A synthetic study on a series of benzimidazole derivatives including cycloalka[b]pyridine moiety has been carried out. Among these compounds synthesized, novel antipeptic agent with 6,7,8,9-tetrahydro-5H- cyclohepta[b]pyridin moiety (TY-11345) was found to be superior to omeprazole in (H++K+)-ATPase inhibitory activity and antisecretory potencies.
Synthetic study of 2-[(6,7,8,9-tetrahydro-5H-cyclohepta[b]pyridin-9-yl)-sulfinyl]-1H-benzimidazole analogs and their biological broperties as novel proton pump inhibitors
Yamada,Goto,Yamaguchi,Aihara,Kogi,Narita
, p. 421 - 431 (1995)
A series of 2-[(cycloalka[b]pyridinyl)sulfinyl]-1H-benzimidazoles (11) was synthesized and tested for antisecretory activity against pentagastrin-induced gastric acid secretion in rats. A novel benzimidazole derivative containing a cyclohepta[b]pyridine m
