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CAS

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157169-73-8

2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 157169-73-8 Structure

  • Basic information

    1. Product Name: 2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine
    2. Synonyms: 2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine
    3. CAS NO:157169-73-8
    4. Molecular Formula: C16H13N3O4
    5. Molecular Weight: 311
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 157169-73-8.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine(157169-73-8)
    11. EPA Substance Registry System: 2-(5-methyl-2-phenyl-4-oxazolylmethoxy)-5-nitropyridine(157169-73-8)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 157169-73-8(Hazardous Substances Data)

157169-73-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 157169-73-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,1,6 and 9 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 157169-73:
(8*1)+(7*5)+(6*7)+(5*1)+(4*6)+(3*9)+(2*7)+(1*3)=158
158 % 10 = 8
So 157169-73-8 is a valid CAS Registry Number.

157169-73-8Relevant articles and documents

Novel 5-substituted-1H-tetrazole derivatives as potent glucose and lipid lowering agents.

Momose,Maekawa, Tsuyoshi,Odaka, Hiroyuki,Ikeda, Hitoshi,Sohda, Takashi

, p. 100 - 111 (2007/10/03)

A series of 5-(4-alkoxyphenylalkyl)-1H-tetrazole derivatives, containing an oxazole-based group at the alkoxy moiety, was prepared and their antidiabetic effects were evaluated in two genetically obese and diabetic animal models, KKAy mice and Wistar fatt

Novel 5-substituted 2,4-thiazolidinedione and 2,4-oxazolidinedione derivatives as insulin sensitizers with antidiabetic activities

Momose, Yu,Maekawa, Tsuyoshi,Yamano, Tohru,Kawada, Mitsuru,Odaka, Hiroyuki,Ikeda, Hitoshi,Sohda, Takashi

, p. 1518 - 1534 (2007/10/03)

Two novel classes of 2,4-thiazolidinediones and 2,4-oxazolidinediones with an ω-(azolylalkoxyphenyl)alkyl substituent at the 5-position were prepared and their antidiabetic effects were evaluated in two genetically obese and diabetic animal models, KKAy mice and Wistar fatty rats. A large number of the 2,4-thia(oxa)zolidinediones showed potent glucose- and lipid-lowering activities. The antidiabetic activities of the 2,4-oxazolidinediones were superior to those of the 2,4-thiazolidinediones. Among the compounds, both enantiomers of 5-[3-[4-[2-(2-furyl)-5-methyl-4-oxazolylmethoxy]-3- methoxyphenyl]propyl]-2,4-oxazolidinedione (64), one of the most interesting compounds in terms of activity, were synthesized by using an asymmetric O-acetylation of the corresponding α-hydroxyvalerate (26) with immobilized lipase, followed by cyclization of the oxazolidinedione ring. (R)-(+)-64 showed more potent glucose-lowering activity (effective dose (ED)25 = 0.561 mg/kg/d) than (S)-(-)-64 (ED25 > 1.5 mg/kg/d) or pioglitazone (ED25 = 6 mg/kg/d) in KKAy mice. It also exhibited a 10-fold more potent antidiabetic activity (ED25 = 0.05 mg/kg/d) than pioglitazone (ED25 = 0.5 mg/kg/d) in Wistar fatty rats. The antidiabetic effects of this compound are considered to be due to its potent agonistic activity for peroxisome proliferator-activated receptor γ (EC50 = 8.87 nM).

Oxazolidinedione derivatives and their use

-

, (2008/06/13)

Novel 2,4-oxazolidinedione compounds of the formula: STR1 wherein R is a hydrocarbon residue or a heterocyclic group each of which may be substituted; Y is --CO--, --CH(OH)-- or --NR3 -- (wherein R3 is an alkyl group which may be substituted); m is 0 or 1; n is 0, 1 or 2; X is CH or N; A is bivalent straight or branched hydrocarbon chain residue having 1 to 7 carbon atoms; R1 and R2 each are hydrogen or an alkyl group, or R1 and R2 are combined with each other to form a 5- to 6-membered heterocyclic group optionally containing nitrogen; L and M each are hydrogen, or L and M are combined with each other to form a bond, or pharmaceutically acceptable salts thereof, having excellent hypoglycemic and hypolipidemic activities and are useful as anti-diabetics or hypolipidemic agents.

Thiazolidinedione derivatives, their production and use

-

, (2008/06/13)

The object of the present invention is to provide a new thiazolidinedione derivative exhibiting excellent hypoglycemic and hypolipidemic action. Thiazolidinedione derivative represented by the general formula: STR1 wherein n represents an integer from 1 t

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