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15718-49-7

GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT, also known as cGMP sodium salt, is a cyclic nucleotide that serves as a second messenger in signal transduction pathways. It is essential in regulating various physiological processes, including smooth muscle relaxation, neurotransmission, platelet aggregation, and retinal phototransduction. cGMP sodium salt is more stable and soluble in aqueous solutions, making it easier to handle and administer in research and pharmaceutical applications.
Used in Pharmaceutical Applications:
GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT is used as a pharmaceutical agent for its role in regulating physiological processes such as smooth muscle relaxation, neurotransmission, platelet aggregation, and retinal phototransduction.
Used in Research Applications:
GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT is used as a research tool for studying cellular signaling and as a reference standard for cGMP measurements.
Used in Biochemical Assays:
GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT is used as a biochemical assay reagent for detecting and quantifying cGMP levels in biological samples.
Used in Drug Development:
GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT is used as a drug development candidate for modulating cGMP levels to treat various diseases and conditions related to cGMP signaling pathways.

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  • Guanosine, cyclic2',3'-(hydrogen phosphate), sodium salt (1:1)

    Cas No: 15718-49-7

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  • 15718-49-7 Structure

  • Basic information

    1. Product Name: GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT
    2. Synonyms: GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT;GUANOSINE-2',3'-CYCLIC MONOPHOSPHATE SODIUM SALT;guanosine 2':3'-cyclic monophosphate*sodium;Guanosine, cyclic 2',3'-(hydrogen phosphate), monosodium salt;guanosine 2',3'-cyclophosphate monosodium salt;Guanosine 2',3'-phosphatesodium salt
    3. CAS NO:15718-49-7
    4. Molecular Formula: C10H11N5O7P*Na
    5. Molecular Weight: 367.19
    6. EINECS: 239-811-1
    7. Product Categories: N/A
    8. Mol File: 15718-49-7.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 778.4°Cat760mmHg
    3. Flash Point: 424.5°C
    4. Appearance: /
    5. Density: 2.64g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: H2O: soluble
    9. CAS DataBase Reference: GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT(CAS DataBase Reference)
    10. NIST Chemistry Reference: GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT(15718-49-7)
    11. EPA Substance Registry System: GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT(15718-49-7)

  • Safety Data

    1. Hazard Codes: Xi
    2. Statements: 36/37/38
    3. Safety Statements: 26-36
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 15718-49-7(Hazardous Substances Data)

15718-49-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 15718-49-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,5,7,1 and 8 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 15718-49:
(7*1)+(6*5)+(5*7)+(4*1)+(3*8)+(2*4)+(1*9)=117
117 % 10 = 7
So 15718-49-7 is a valid CAS Registry Number.

15718-49-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name GUANOSINE 2':3'-CYCLIC MONOPHOSPHATE SODIUM SALT

1.2 Other means of identification

Product number -
Other names 2':3'-Cycloguanosinphosphat

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:15718-49-7 SDS

15718-49-7Downstream Products

15718-49-7Relevant articles and documents

Phosphorylation, oligomerization and self-assembly in water under potential prebiotic conditions

Gibard, Clémentine,Bhowmik, Subhendu,Karki, Megha,Kim, Eun-Kyong,Krishnamurthy, Ramanarayanan

, p. 212 - 217 (2018/02/06)

Prebiotic phosphorylation of (pre)biological substrates under aqueous conditions is a critical step in the origins of life. Previous investigations have had limited success and/or require unique environments that are incompatible with subsequent generation of the corresponding oligomers or higher-order structures. Here, we demonstrate that diamidophosphate (DAP) - a plausible prebiotic agent produced from trimetaphosphate - efficiently (amido)phosphorylates a wide variety of (pre)biological building blocks (nucleosides/tides, amino acids and lipid precursors) under aqueous (solution/paste) conditions, without the need for a condensing agent. Significantly, higher-order structures (oligonucleotides, peptides and liposomes) are formed under the same phosphorylation reaction conditions. This plausible prebiotic phosphorylation process under similar reaction conditions could enable the systems chemistry of the three classes of (pre)biologically relevant molecules and their oligomers, in a single-pot aqueous environment.

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