157372-85-5Relevant articles and documents
Stereoselective synthesis of dienylamines: From amino acids to E-alkene dipeptide isosters
Reginato, Gianna,Gaggini, Francesca,Mordini, Alessandro,Valacchi, Michela
, p. 6791 - 6800 (2007/10/03)
A stereoselective approach to dienylamines is described, starting from enantiomerically enriched stannylated allylamines, which are in turn derived from amino acids. Conveniently the procedure allows to introduce diversity at 1-,2- and 4- positions of the final compounds. Conversion to vinylstannane has been extended to dipeptido aldehydes. The possible elaboration of 4-methyl substituted dienylamines to Boc-Gly-Ψ[(E)-CHCH]-(l,d)-Ala and Boc-Phe -Ψ[(E)-CHCH]-(l,d)-Ala dipeptide isosters is also shown.
8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives
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, (2008/06/13)
The present invention relates to new 8-amino-10-(azabicycloalkyl)-pyrido?1,2,3-d,e!?1,3,4!benzoxadiazine derivatives of the general formula (I) STR1 in which the radicals R1 to R4, Z and X1 have the meaning given in the description, processes for their preparation and their use in antibacterial compositions.
Pyrido[1,2,3-D,E] [1,3,4]benzoxadiazine derivatives
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, (2008/06/13)
Novel bactericidal pyrido[1,2,3-d,e,][1,3,4]benzoxadiazine derivatives of the formula (I) STR1 in which R1 is hydrogen or C1 -C4 -alkyl optionally substituted by hydroxyl or halogen, R2 independently of R1
7-isoindolinyl-naphthyridone derivatives, compositions and anti-bacterial use thereof
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, (2008/06/13)
The invention relates to novel quinolone derivatives and naphthyridone derivatives which are substituted in the 7-position by a partially hydrogenated isoindolinyl ring, to processes for their preparation and to antibacterial agents and feed additives containing them.
Quinolone- and naphthyridonecarboxylic acid derivatives
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, (2008/06/13)
The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which have hydrogen in the 6-position, to processes for their preparation, and to antibacterial compositions and feed additives containing them.
7-isoindolinyl-quinolone-carboxylic acid derivatives
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, (2008/06/13)
The invention relates to new quinolone- and naphthyridonecarboxylic acid derivatives which are substituted in the 7-position by a partly hydrogenated isoindolinyl ring, processes for their preparation and antibacterial agents and feed additives containing