157431-96-4

Basic information

• Product Name: 2-Azetidinone,3-amino-1-(1-propenyl)-(9CI)
• Synonyms: 2-Azetidinone,3-amino-1-(1-propenyl)-(9CI)
• CAS NO: 157431-96-4
• Molecular Formula: C6H10N2O
• Molecular Weight: 126.1564
• Product Categories: AMINETERTIARY;AMINEPRIMARY
• Mol File: 157431-96-4.mol

Chemical Properties

• Boiling Point: 263.4±29.0 °C(Predicted)
• Appearance: /
• Density: 1.236±0.06 g/cm3(Predicted)
• PKA: 6.65±0.20(Predicted)
• CAS DataBase Reference: 2-Azetidinone,3-amino-1-(1-propenyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Azetidinone,3-amino-1-(1-propenyl)-(9CI)(157431-96-4)
• EPA Substance Registry System: 2-Azetidinone,3-amino-1-(1-propenyl)-(9CI)(157431-96-4)

Safety Data

• Hazardous Substances Data: 157431-96-4(Hazardous Substances Data)

Usage

Also Known As

l-(1-allyl)-3-aminopyrrolidin-2-one

Derivative Of

Pyrrolidin-2-one

Physical State

White solid

Molecular Weight

126.15 g/mol

Primary Use

Intermediate in the synthesis of pharmaceuticals and agrochemicals

Versatility

Due to its chemical structure and properties, it serves as a versatile building block in organic synthesis

Chelating Agent

Used in metal ion extraction and separation processes

Applications in Medicinal Chemistry

Potential applications in the development of new drugs

Value

Considered a valuable chemical with diverse industrial and scientific uses

Upstream product

• 199385-26-7 2-(1-Allyl-2-oxo-azetidin-3-yl)-isoindole-1,3-dione 
• 26028-43-3 1,3,5-triallylhexahydro-1,3,5-triazine 
• 157431-96-4 (R)-3-Amino-1-N-(propen-1-yl)azetidin-2-one 
• 157431-96-4 3-Amino-1-N-(propen-1-yl)azetidin-2-one 

Downstream Products

• 157431-96-4 (R)-3-Amino-1-N-(propen-1-yl)azetidin-2-one 
• 157431-96-4 (S)-3-Amino-1-N-(propen-1-yl)azetidin-2-one 
• 157431-96-4 3-Amino-1-N-(propen-1-yl)azetidin-2-one 

Relevant articles and documents

Temperature and solvent effects on enzyme stereoselectivity: Inversion temperature in kinetic resolutions with lipases

Eyring plots of InE vs. 1/T show inversion temperature in kinetic resolution by lipases, demonstrating that clustering effects in the substrate solvation manage the enzymatic selectivity.

A total synthesis of (1R,5R)-3-phenylmethyl-4-thia-2,6-diazabicyclo [3.2.0]hept-2-en-7-one, a useful intermediate for the preparation of penem and cepham derivatives

The preparation of the thiazoline (1R,5R)-3-phenylmethyl-4-thia-2,6- diazabicyclo [3.2.0]hept-2-en-7-one (1) is presented. This compound, which has been extensively used as an intermediate for the synthesis of penems and cephams, has been obtained starting from a C-4 unsubstituted azetidinone by means of facile processes while chirality has been obtained through enzymatic resolution.