Studies on the Role of the 2-Oxonia Cope Rearrangement in ?-Cyclizations of α-Methoxycarbonyl Oxycarbenium Ions
The 2-oxonia Cope rearrangement is shown to play an important role in Lewis acid-induced ?-cyclization reactions of a variety of methyl 2-acetoxy-2-(3-alken-1-oxy)acetates to 5- and 6-membered ring ethers.The influence of this -sigmatropic rearrangem
Lolkema, Lucie D. M.,Semeyn, Cindy,Ashek, Loulou,Hiemstra, Henk,Speckamp, W. Nico