158261-95-1

Basic information

• Product Name: 3-(1-PYRROLIDINYL)-1-BUTANOL
• Synonyms: 3-(1-pyrrolidinyl)-1-butanol(SALTDATA: FREE);3-Pyrrolidin-1-ylbutan-1-ol;g-Methyl-1-Pyrrolidinepropanol;3-1-pyrrolidinylbutan-1-ol;3-(1-PYRROLIDINYL)-1-BUTANOL
• CAS NO: 158261-95-1
• Molecular Formula: C8H17NO
• Molecular Weight: 143.23
• Mol File: 158261-95-1.mol

Chemical Properties

• Boiling Point: 227.924°C at 760 mmHg
• Flash Point: 96.509°C
• Appearance: /
• Density: 0.982g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.488
• Storage Temp.: 2-8°C
• PKA: 15.00±0.10(Predicted)
• CAS DataBase Reference: 3-(1-PYRROLIDINYL)-1-BUTANOL(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(1-PYRROLIDINYL)-1-BUTANOL(158261-95-1)
• EPA Substance Registry System: 3-(1-PYRROLIDINYL)-1-BUTANOL(158261-95-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 158261-95-1(Hazardous Substances Data)

Usage

Uses

Used in Fragrance Industry:
3-(1-PYRROLIDINYL)-1-BUTANOL is used as a fragrance ingredient for its ability to impart a slightly sweet, floral odor to various consumer products, enhancing their sensory appeal.
Used in Solvent Applications:
In the manufacturing process, 3-(1-PYRROLIDINYL)-1-BUTANOL is used as a solvent for resins, facilitating the production of various industrial materials.
Used in Perfume and Personal Care Products:
3-(1-PYRROLIDINYL)-1-BUTANOL is used as a stabilizer and fixative in perfumes, soaps, and other personal care products to maintain the integrity and longevity of the fragrances.
Used in Pharmaceutical Industry:
3-(1-PYRROLIDINYL)-1-BUTANOL is used as a chiral auxiliary in the pharmaceutical industry, playing a crucial role in the synthesis of enantiomerically pure compounds, which is vital for drug development and efficacy.
Given its low toxicity and minimal adverse effects on human health and the environment, 3-(1-PYRROLIDINYL)-1-BUTANOL is a versatile compound with a broad range of applications. However, it is essential to handle it with care and follow proper safety guidelines to ensure its safe and effective use.

InChI:InChI=1/C8H17NO/c1-8(4-7-10)9-5-2-3-6-9/h8,10H,2-7H2,1H3

Upstream product

• 42980-67-6 Ethyl 3-pyrrolidinobutyrate 
• 70526-06-6 (Z)-3-pyrrolidin-1-yl-but-2-enoic acid ethyl ester 

Relevant articles and documents

3- Or 4-monosubstituted phenol derivatives useful as H3 ligands

The invention relates to 3- or 4-monosubstituted phenol derivatives and to processes for the preparation of, intermediates used in the preparation of, compositions containing and the uses of, such derivatives. Said 3- or 4-monosubstituted phenol derivatives are H3 ligands and are useful in numerous diseases, disorders and conditions, in particular inflammatory, allergic and respiratory diseases, disorders and conditions.

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In a recent study, racemic 3-(N,N-dimethylamino)butyl-N,N-dimethylcarbamate (1) was shown to be a potent agonist at neuronal nicotinic acetylcholine receptors with a high selectivity for nicotinic over muscarinic acetylcholine receptors [Mol. Pharmacol. 6

Chemo- and diastereoselective reduction of β-enamino esters: A convenient synthesis of both cis- and trans-γ-amino alcohols and β-amino esters

Convenient procedures for the chemo- and diastereoselective reduction of b-enamino esters 1 are described. Both cis- and trans-γ-amino alcohols 2 or b-amino esters 3 can be prepared by reduction of b-enamino esters 1, readily available starting materials, with the use of inexpensive reagents Na/i-PrOH or NaHB(OAc)3/AcOH, respectively, and the appropriate reduction conditions. The mechanisms and diastereoselectivities for the reductions are discussed. The relative configurations and conformations of the diastereoisomeric γ-amino alcohols 2 and β-amino esters 3 obtained are established by 1H and 13C NMR study and unequivocally set by their cyclic derivatives tetrahydro-1,3-oxazines 4.