Chemoenzymatic Synthesis of 4-Substituted Riboses. S-(4'-Methyladenosyl)-L-homocysteine
The synthesis of 4-C-methyl-D-ribose, 4-C-phenyl-D-ribose, D-ribose-4-d, and L-ribose derivatives as well as the title nucleoside by a chemoenzymatic strategy beginning from cyclopentadiene is described.
Johnson, Carl R.,Esker, John L.,Zandt, Michael C. Van