Identification of a novel conformationally constrained glucagon receptor antagonist
Identification of orally active, small molecule antagonists of the glucagon receptor represents a novel treatment paradigm for the management of type 2 diabetes mellitus. The present work discloses novel glucagon receptor antagonists, identified via confo
Lee, Esther C.Y.,Tu, Meihua,Stevens, Benjamin D.,Bian, Jianwei,Aspnes, Gary,Perreault, Christian,Sammons, Matthew F.,Wright, Stephen W.,Litchfield, John,Kalgutkar, Amit S.,Sharma, Raman,Didiuk, Mary T.,Ebner, David C.,Filipski, Kevin J.,Brown, Janice,Atkinson, Karen,Pfefferkorn, Jeffrey A.,Guzman-Perez, Angel
p. 839 - 844
(2014/02/14)
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