Concise total synthesis of (+)-WIN 64821 and (-)-ditryptophenaline
(Chemical Equation Presented) On a fast track: The secondary metabolites (+)-WIN 64821 and (-)-ditryptophenaline have been synthesized in six and seven steps, respectively, from amino acid derivatives in a concise and enantioselective manner. The gram-scale synthesis of key intermediates and the simultaneous introduction of vicinal quaternary stereocenters are described. The synthesis and structural confirmation of (-)-1′-(2-phenylethylene) ditryptophenaline is also reported.
Movassaghi, Mohammad,Schmidt, Michael A.,Ashenhurst, James A.
p. 1485 - 1487
(2008/12/22)
More Articles about upstream products of 159355-77-8