Pd-catalyzed oxidative annulation of hydrazides with isocyanides: Synthesis of 2-amino-1,3,4-oxadiazoles
An efficient palladium-catalyzed oxidative annulation reaction was developed through sequential isocyanide insertions into N-H and O-H bonds of hydrazides, which provides an efficient access to valuable 2-amino-1,3,4- oxadiazoles and their derivatives.
Fang, Tao,Tan, Qitao,Ding, Zhengwei,Liu, Bingxin,Xu, Bin
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p. 2342 - 2345
(2014/05/20)
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